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Dosing Optimization of Beta-Lactam Antibiotics using Parametric and Nonparametric Population Pharmacokinetic Models

Author: Femke Velde
Publisher: Erasmus University Rotterdam 2020-10-14
Edition/Format: Book Book : English
Summary:
This thesis is mainly focused on dosing evaluation of old antibiotics using parametric and nonparametric population pharmacokinetic models. Additionally, modelling-related challenges during dosing evaluation were identified and recommendations on the use of these models during drug development and in clinical practise were set up.
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Document Type: Book
All Authors / Contributors: Femke Velde
ISBN: 978-94-6332-620-9
Language Note: English
Unique Identifier: 8689828874
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Abstract:

This thesis is mainly focused on dosing evaluation of old antibiotics using parametric and nonparametric population pharmacokinetic models. Additionally, modelling-related challenges during dosing evaluation were identified and recommendations on the use of these models during drug development and in clinical practise were set up.

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