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Drug discovery handbook

Author: Shayne C Gad
Publisher: Hoboken, N.J. : Wiley-Interscience, ©2005.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and  Read more...
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Genre/Form: Electronic books
Handbooks and manuals
Handbooks, manuals, etc
Guides, manuels, etc
Additional Physical Format: Print version:
Drug discovery handbook.
Hoboken, N.J. : Wiley-Interscience, ©2005
(DLC) 2004027077
(OCoLC)57001932
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Shayne C Gad
ISBN: 0471728772 9780471728771 0471728780 9780471728788
OCLC Number: 609350479
Reproduction Notes: Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (xix, 1471 pages) : illustrations
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: Drug discovery in the 21st century --
Natural products / Charles B. Spainhour --
Cancer cell proteomics using molecular aptamers / Weihong Tan [and others] --
Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath --
Systems biology : applications in drug discovery / Sean Ekins [and others] --
High throughput flow cytometry / Larry A. Sklar [and others] --
Combining NMR spectral information with associated structural features to form computationally nonintensive, rugged, and objective models of biological activity / Richard D. Beger, Dan A. Buzatu, and Jon G. Wilkes --
Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, and William Neil. Age of regulation / Sandy Weinberg and Gerald J. Whartenby --
Simultaneous screening of multiple cell lines using the CellCard system / Oren E. Beske --
Protein X-ray crystallography in drug discovery / Peter Nollert [and others] --
Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings --
Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian and Giorgio Palù --
High-throughput screening : evolution of technology and methods --
Martyn N. Banks [and others] --
Metal-enhanced fluorescence : application to high-throughput screening and drug discovery / Kadir Aslan [and others]. Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood [and others] --
Coupled luminescent methods in drug discovery : 3-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey and Robert J. Kinders --
Design and pharmaceutical applications of prodrugs / Tomi Järvinen [and others] --
GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen [and others] --
Cardiac sarcolemmal ATP-sensitive potassium channel antagonists : novel ischemia-selective antiarrhythmic agents / George E. Billman. Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid, and anticoagulant therapies for sepsis / Peter C. Minneci [and others] --
Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, and Benjamin L. Miller --
Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho and J.K.S. Ko --
Endocrine and metabolic agents / Brian L. Furman --
Respiratory viruses / Paul D. Olivo --
Strategies in the design of antiviral drugs / Erik De Clercq and Piet Herdewijn --
Protein kinase inhibitors in drug discovery / Keykavous Parang and Gongqin Sun --
RNA-based therapies / Steve Pascolo --
Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov and Zaver M. Bhujwalla --
Targets and approaches for cancer drug discovery / Susan L. Mooberry.
Responsibility: edited by Shayne Cox Gad.
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Abstract:

Offers the techniques and methods in drug discovery, including genomics. This practical guide presents an explanation of proteomics, high throughput screening, and systems biology.  Read more...

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"...provides in one volume most of the currently used and emerging technologies available...presents a wealth of information on topics that are difficult to find elsewhere...a very useful handbook." Read more...

 
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