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Dynamic-clamp : from principles to applications

Author: Alain Destexhe; Thierry Bal
Publisher: New York ; London : Springer, ©2009.
Series: Springer series in computational neuroscience, v. 1.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called "conductance injection") allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer. The technique can be implemented from neural simulation environments and a variety of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Dynamic-clamp.
New York : Springer, ©2009
(DLC) 2008942719
(OCoLC)288985484
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Alain Destexhe; Thierry Bal
ISBN: 9780387892795 0387892796 9780387892788 0387892788
OCLC Number: 341597733
Description: 1 online resource (xiv, 429 pages) : illustrations.
Contents: Associating Living Cells and Computational Models: an Introduction to Dynamic Clamp Principles and its Applications --
Dendritic Dynamic Clamp – A Tool to Study Single Neuron Computation --
Synaptic Conductances and Spike Generation in Cortical Cells --
Simulating In Vivo Background Activity in a Slice with the Dynamic Clamp --
Impact of Background Synaptic Activity on Neuronal Response Properties Revealed by Stepwise Replication of In Vivo-Like Conditions In Vitro --
Testing Methods for Synaptic Conductance Analysis Using Controlled Conductance Injection with Dynamic Clamp --
In Vivo Dynamic-Clamp Manipulation of Extrinsic and Intrinsic Conductances: Functional Roles of Shunting Inhibition and I BK in Rat and Cat Cortex --
Functions of the Persistent Na+ Current in Cortical Neurons Revealed by Dynamic Clamp --
Using “Hard” Real-Time Dynamic Clamp to Study Cellular and Network Mechanisms of Synchronization in the Hippocampal Formation --
Unraveling the Dynamics of Deep Cerebellar Nucleus Neurons with the Application of Artificial Conductances --
Intrinsic and Network Contributions to Reverberatory Activity: Reactive Clamp and Modeling Studies --
Dynamic-Clamp-Constructed Hybrid Circuits for the Study of Synchronization Phenomena in Networks of Bursting Neurons --
Using the Dynamic Clamp to Explore the Relationship Between Intrinsic Activity and Network Dynamics --
Re-Creating In Vivo-Like Activity and Investigating the Signal Transfer Capabilities of Neurons: Dynamic-Clamp Applications Using Real-Time Neuron --
Using the Dynamic Clamp to Dissect the Properties and Mechanisms of Intrinsic Thalamic Oscillations --
Dynamic Clamp with High-Resistance Electrodes Using Active Electrode Compensation In Vitro and In Vivo --
Key Factors for Improving Dynamic-Clamp Performance --
Development of a Genetically Engineered Cardiac Pacemaker: Insights from Dynamic Action Potential Clamp Experiments.
Series Title: Springer series in computational neuroscience, v. 1.
Responsibility: edited by Alain Destexhe, Thierry Bal.

Abstract:

Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. This book contains contributions from leading researchers who address a  Read more...

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