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Details
Document Type: | Book |
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All Authors / Contributors: | Marlijn Vermeiden |
ISBN: | 978-94-6299-894-0 |
Language Note: | English |
Unique Identifier: | 8086657111 |
Awards: |
Abstract:
textabstractThe main aim of this thesis was to evaluate the efficacy of three phases of a treatment algorithm of inpatients with severe depression: phase I optimal antidepressant monotherapy (plasma level targeted dose imipramine or high-dose (375 mg/day) venlafaxine); phase II subsequent lithium addition in case of insufficient improvement of antidepressant monotherapy; phase Ill subsequent ECT in case of insufficient improvement of antidepressant-lithium treatment. Additionally, this thesis aims to further investigate predictors of antidepressant treatment response, i.e. early drug response, gender and menopausal status.
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