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Enabling novel treatments for nervous system disorders by improving methods for traversing the blood-brain barrier : proceedings of a workshop

Author: Lisa J Bain; Noam I Keren; Clare Stroud; National Academies of Sciences, Engineering, and Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders,
Publisher: Washington, DC : The National Academies Press, [2018] ©2018
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the blood-brain barrier (BBB). The  Read more...
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Genre/Form: Congress
Electronic books
Conference papers and proceedings
Congresses
Additional Physical Format: Print version:
Bain, Lisa J.
Enabling novel treatments for nervous system disorders by improving methods for traversing the bloodƠbrain barrier.
Washington, D.C. : National Academies Press, [2018]
(OCoLC)1030592949
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Lisa J Bain; Noam I Keren; Clare Stroud; National Academies of Sciences, Engineering, and Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders,
ISBN: 9780309473088 030947308X 9780309473101 0309473101
OCLC Number: 1039702209
Description: 1 online resource (xii, 59 pages) : color illustrations
Contents: Introduction and overview --Traversing the blood-brain barrier : challenges and opportunities --
Modalities and technologies for brain delivery --
Regulatory considerations for drugs that traverse the blood-brain barrier --
Accelerating research and clinical translation : consortia and public-private partnerships --
Appendixes.
Responsibility: Lisa Bain, Noam I. Keren, and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine.

Abstract:

"Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the blood-brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.

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