Epidemiology and treatment effects in Chronic Obstructive Pulmonary Disease (Book, 2011) [WorldCat.org]
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Epidemiology and treatment effects in Chronic Obstructive Pulmonary Disease

Author: Ana Afonso
Publisher: Erasmus University Rotterdam 2011-04-15
Edition/Format: Book Book : English
Summary:
textabstractChronic obstructive pulmonary disease (COPD) is a major health epidemic, which has importantconsequences for patients and community, and still receives insufficient attention fromthe health care professionals and scientists. COPD is a leading cause of chronic morbidity(affects 210 million people) and mortality (causes 3 million deaths per year) worldwide, and according to the World Health Organization  Read more...
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Details

Document Type: Book
All Authors / Contributors: Ana Afonso
ISBN: 978-94-6169-033-3
Language Note: English
Unique Identifier: 6892893212
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Abstract:

textabstractChronic obstructive pulmonary disease (COPD) is a major health epidemic, which has importantconsequences for patients and community, and still receives insufficient attention fromthe health care professionals and scientists. COPD is a leading cause of chronic morbidity(affects 210 million people) and mortality (causes 3 million deaths per year) worldwide, and according to the World Health Organization (WHO), it is the fifth most common causeof death and the 10th most burdensome disease.The first definition of chronic obstructive pulmonary disease (COPD) can be found in the 60’sand incorporates both terms “emphysema” and “chronic bronchitis”.According to the Global Initiative for obstructive lung diseases (GOLD), COPD is definedas a “preventable and treatable disease with some significant extra-pulmonary effects thatmay contribute to the severity in individual patients. The pulmonary component is characterizedby airflow limitation, which is not fully reversible. The airflow limitation is usuallyprogressive and associated with an abnormal inflammatory response of the lungs to noxiousparticles or gases, such as cigarette smoke”. COPD is clinically characterized by symptomslike cough, sputum production, and/or dyspnea. The diagnosis is confirmed by spirometryand accordingly has four stages, from mild (GOLD stage I) to very severe (GOLD stage IV). Patients with COPD typically have a decrease in both FEV1 and a FEV1/FVC ratio of lessthan 0.7. Using this ratio as cut-off point for all patients is currently questioned as it mayunderestimate COPD in the young and overestimate COPD in older populations.The GOLD definition has become globally accepted for the diagnosis of COPD and somecrucial components of this definition have been incorporated by the European RespiratorySociety (ERS) and by the American Thoracic Society (ATS).

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