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Epigenetics for drug discovery

Author: Nessa Carey
Publisher: Cambridge Royal Society of Chemistry [2016]
Series: RSC drug discovery, no. 48
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

This book will provide an invaluable guide to epigenetics, one of the fastest moving fields in drug discovery, for medicinal chemists working in academia and in the pharmaceutical industry.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Nessa Carey
ISBN: 9781849738828 1849738823
OCLC Number: 940748125
Description: xv, 321 Seiten : Illustrationen.
Contents: Epigenetics - What it is and Why it Matters; Enzyme and Protein Families that Regulate Histone Modifications and Crosstalk; Epigenetics and Disease; Targeting DNA Methylation; Targeting Histone Acetylation; Targeting Histone Lysine Methyltransferases in Cancer; Targeting Non-Acetylation Histone Erasers; Progress in Targeting Epigenetic Readers; Who will Bebefit from Epigenetic Drugs; Dosing - When Less Is More; Histone Methyltransferase Activity Assays; Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose?;
Series Title: RSC drug discovery, no. 48
Responsibility: edited by Nessa Carey.

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This book provides a rather compact overview to the field which will be very useful to medicinal chemists who want to get a short introduction into the field but also biologists who want to learn Read more...

 
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