Essentials of stem cell biology (eBook, 2009) [WorldCat.org]
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Essentials of stem cell biology
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Essentials of stem cell biology

Author: Robert Paul Lanza; et al
Publisher: San Diego, CA ; London, UK : Academic Press, 2009.
Edition/Format:   eBook : Document : English : 2nd ed
Summary:
First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of  Read more...
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Genre/Form: Electronic books
Textbooks
Material Type: Document
Document Type: Book, Computer File
All Authors / Contributors: Robert Paul Lanza; et al
ISBN: 9780123747297 0123747295
OCLC Number: 858755809
Description: 1 online resource (xxix, 650 p.) : ill. (chiefly col.)
Contents: FOREWORD --
Why Stem Cell Research? --
A New Path?{ Induced Pluripotent Stem Cells --
Embryonic Stem Cells Versus Adult Stem Cells --
'Stemness': Definitions, Criteria and Standards --
PART ONE --
INTRODUCTION TO STEM CELLS --
1. Present Perspective and Future Challenges --
2. Embryonic Stem Cells in Perspective --
3. The Development of Epithelial Stem Cell Concepts --
4. The Advent of Direct Reprogramming --
5. Clinical Translation of Stem Cells --
PART TWO --
BASIC BIOLOGY/MECHANISMS --
6. Molecular Basis of Pluripotency --
7. Stem Cell Niches --
8. Mechanisms of Stem Cell Self-Renewal --
9. Cell Cycle Regulators in Stem Cells --
10. Epigenetic Mechanisms of Cellular Memory --
11. Cell Fusion and the Differentiated State --
12. How Cells Change Their Phenotype --
PART THREE --
TISSUE AND ORGAN DEVELOPMENT --
13. Differentiation in Early Development --
14. Primordial Germ Cells in Mouse and Human --
15. Stem Cells in Extraembryonic Lineages --
16. Amniotic Fluid Derived Pluripotent Cells --
17. Cord Blood Stem Cells --
18. Neurogenesis in the Vertebrate Embryo --
19. The Nervous System --
20. Neuronal Progenitors in the Adult Brain --
21. Sensory Epithelium of the Eye and Ear --
22. Epithelial Skin Stem Cells --
23. The Ontogeny of the Hematopoietic System --
24. Hematopoietic Stem Cells --
25. Red Blood Cells --
26. Cell Differentiation in the Skeleton --
27. Vascular Progenitor Cells --
28. Multipotent Adult Progenitor Cells --
29. Mesenchymal Stem Cells --
30. Skeletal Muscle Stem Cells --
31. Stem Cells and the Regenerating Heart --
32. Potential of ES Cell Differentiation Culture for Vascular Biology --
33. Cell Lineages and Stem Cells in the Kidney --
34. Adult Liver Stem Cells --
35. Pancreatic Stem Cells --
36. Stem Cells in the Gastrointestinal Tract --
37. Stem Cells in the Lung --
PART FOUR --
METHODS --
38. Generation of Induced Pluripotent Stem Cells --
39. Characteristics and Characterization of Pluripotent Stem Cells --
40. Isolation and Maintenance of Murine Embryonic Stem Cells --
41. Isolation, Characterization, and Maintenance of Primate ES Cells --
42. Approaches for Derivation and Maintenance of Human ES cells: --
Detailed Procedures and Alternatives --
43. Derivation and Differentiation of Human EG Cells --
44. Growth Factors & the Serum-Free Culture of Human Pluripotent Stem Cells --
45. Feeder-Free Culture --
46. Genetic Manipulation of Human Embryonic Stem Cells --
47. Homologous Recombination in Human Embryonic Stem Cells --
48. Surface Antigen Markers --
49. Lineage Marking --
50. Genomic Reprogramming --
51. Isolation and Characterization of Hematopoietic Stem Cells --
52. Microarray Analysis of Stem Cells and Differentiation --
53. Zebrafish and Stem Cell Research --
PART FIVE --
APPLICATIONS --
54. Cancer Stem Cells --
55. Neural Stem Cells: Therapeutic Applications in Neurodegenerative Diseases --
56. Spinal Cord Injury --
57. Use of Embryonic Stem Cells to Treat Heart Disease --
58. Insulin-Producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes --
59. Burns and Skin Ulcers 978-0-12-370465-8...
Responsibility: editors, Robert Lanza ... [et al.].

Abstract:

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. * Contributions by Nobel Laureates and leading international investigators * Includes two entirely new chapters devoted exclusively to iPS written by the scientists who made the breakthroug * Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate.

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