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Genre/Form: | Thèses et écrits académiques |
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Material Type: | Document, Thesis/dissertation |
Document Type: | Computer File |
All Authors / Contributors: |
Jessica Save-Pédebos; Isabelle Jambaqué; Sylvain Moutier; Arnaud Roy, neuropsychologue).; Yves Chaix; Christine Bulteau-Peyrie; Université Sorbonne Paris Cité.; École doctorale Cognition, comportements, conduites humaines (Boulogne-Billancourt, Hauts-de-Seine).; Université Paris Descartes (1970-2019). |
OCLC Number: | 1250320257 |
Notes: | Titre provenant de l'écran-titre. |
Description: | 1 online resource |
Responsibility: | Jessica Save-Pédebos ; sous la direction de Isabelle Jambaqué. |
Abstract:
Children with medically refractory epilepsy caused by extensive hemispheric lesions are the best candidate for hemispherotomy in order to cure epilepsy. It leads the patient to the amazing situation of living with the one controlateral isolated and safe hemisphere. The topic of this research concerns pragmatic and emotional aspects of language in a large population of 40 hemispherotomized children. Our aim was to study development of language, peculiarly pragmatic skills and emotion comprehension, and analyse their socio-cognitive profile according to side and age at surgery, considering hemispheric specialization and developmental cognitive plasticity. Pragmatic disorders were found in 40% of patients. More frequent pragmatic disorders were observed after right hemispherotomy among children operated after the age of 18 months, independently of lexical or syntactic comprehension. We demonstrated a correlation between pragmatic language impairment and deficits in executive functions. We showed a long term deficit in facial emotion recognition abilities in this population. Finally, the longer was the duration of epilepsy and the later was the surgery, the worst was their emotion comprehension of stories, promoting early surgery to improve their linguistic and socio-cognitive development.
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