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Eukaryotic RNases and their partners in RNA degredation and biogenesis. Part B

Author: Feng Guo, (Biochemist); Fuyuhiko Tamanoi
Publisher: Amsterdam : Elsevier, 2012.
Series: Enzymes, v. 32.
Edition/Format:   Print book : English : First editionView all editions and formats
Summary:

Suitable for researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this book discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.

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Document Type: Book
All Authors / Contributors: Feng Guo, (Biochemist); Fuyuhiko Tamanoi
ISBN: 9780124047419 0124047416
OCLC Number: 1125279523
Description: x, 229 pages : illustrations (some color) ; 24 cm.
Contents: Dicer proteins and their role in gene silencing pathways --
Loquacious, a dicer partner protein, functions in both the microRNA nad siRNA pathways --
Translin: TRAX complex (C3PO), a novel ribonuclease for the degradation of small RNAs --
Structure and mechanism of Argonaute proteins --
Drosha and DGCR8 in microRNA biogenesis --
Control of Drosha-mediated microRNA maturation by Smad proteins --
PIWI proteins and their slicer activity in piRNA biogenesis and transposon silencing --
Control of microRNA maturation by p53 tumor suppressor and MCPIP1 ribonuclease --
Nanoparticle-based delivery of siRNA and miRNA for cancer therapy.
Series Title: Enzymes, v. 32.
Responsibility: edited by Feng Guo (Department of Biological Chemistry, David Geffen School of Medicine, Molecular Biology Institute, University of California, Los Angeles, CA), Fuyuhiko Tamanoi (Department of Microbiology, Immunology, and Molecular Genetics, Molecular Biology Institute, University of California, Los Angeles, CA).

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