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Ex vivo cell therapy

Author: Klaus Schindhelm; Robert Nordon
Publisher: San Diego : Academic Press, ©1999.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, or  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Ex vivo cell therapy.
San Diego : Academic Press, ©1999
(DLC) 98089643
(OCoLC)42398064
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Klaus Schindhelm; Robert Nordon
ISBN: 9780126249606 0126249601 9780080531335 0080531334
OCLC Number: 162129210
Reproduction Notes: Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (xix, 356 pages) : illustrations
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: R.E. Nordon and K. Schindhelm, Introduction. --
L. Robb, A.G. Elefanty, and C.G. Begley, Transcriptional Control of Hematopoieses. --
R. Starr and N.A. Nicola, Cell Signaling by Hemopoietic Growth Factor Receptors. --
P.J. Simmons, D.N. Haylock, and J.-P. Lévesque, Influence of Cytokines and Adhesion Molecules on Hematopoietic Stem Cell Development. --
P.A. Rowlings, Allogeneic Hematopoietic Stem Cell Transplantation. --
U. Hahn and L.B. To, Autologous Stem Cell Transplantation. --
M.R. Vowels, Cord Blood Stem Cell Transplantation. --
S.R. Riddell, E.H. Warren, D. Lewinsohn, C. Yee, and P.D. Greenberg, Reconstitution of Immunity by Adoptive Immunotherapy with T Cells. --
L.Q. Sun, M. Miller, and G. Symonds, Exogenous Gene Transfer into Lymphoid and Hematopoietic Progenitor Cells. --
C. Dowding, T. Leemhuis, A. Jakubowski, and C. Reading, Process Development for Ex Vivo Cell Therapy. --
R.E. Nordon and K. Schindhelm, Cell Separation. --
P.W. Zandstra, C.J. Eaves, and J.M. Piret, Environmental Requirements of Hematopoietic Progenitor Cells in Ex Vivo Expansion Systems. --
R. Mandalam, M. Koller, and A. Smith, Ex Vivo Hematopoietic Cell Expansion for Bone Marrow Transplantation. --
M. Raponi and G. Symonds, Gene Delivery Technology: Nonviral and Viral Vector Systems. --
R.E. Nordon and K. Schindhelm, Summary and Future Directions. --
Index. Sec. 1. Introduction --
Sec. 2. Transcriptional control of hematopoiesis --
Sec. 3. Cell signaling by hematopoietic growth factor receptors --
Sec. 4. Influence of cytokines and adhesion molecules on hematopoietic stem cell development --
Sec. 5. Allogeneic hematopoietic stem cell transplantation --
Sec. 6. Autologous stem cell transplantation --
Sec. 7. Cord blood stem cell transplantation --
Sec. 8. Reconstitution of immunity by adoptive immunotherapy with T cells --
Sec. 9. Exogenous gene transfer into lymphoid and hematopoietic progenitor cells --
Sec. 10. Process development for ex vivo cell therapy --
Sec. 11. Cell separation --
Sec. 12. Environmental requirements of hematopoietic progenitor cells in ex vivo expansion systems --
Sec. 13. Ex vivo hematopoietic cell expansion for bone marrow transplantation --
Sec. 14. Gene delivery technology: nonviral and viral vector systems --
Sec. 15. Summary and future directions.
Responsibility: edited Klaus Schindhelm, Robert Nordon.
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Abstract:

Integrates the advances in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers, biotechnologists and biomedical  Read more...

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Primary Entity

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