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Extracellular Matrix Assembly and Structure.

Author: Peter D Yurchenco; Robert P Mecham; David E Birk
Publisher: Burlington : Elsevier Science, 1994.
Series: Biology of extracellular matrix.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell,  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Yurchenco, Peter D.
Extracellular Matrix Assembly and Structure.
Burlington : Elsevier Science, ©1994
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Peter D Yurchenco; Robert P Mecham; David E Birk
ISBN: 9781483289427 1483289427
OCLC Number: 893740408
Notes: II. Elastin Fiber Composition.
Description: 1 online resource (483 pages).
Contents: Front Cover; Extracellular Matrix Assembly and Structure; Copyright Page; Table of Contents; CONTRIBUTORS; PREFACE; Chapter 1. Concepts of Self-Assembly in Biological Systems; I. Introduction; II. Linear Aggregation Models; III. Equilibrium Treatment; IV. Kinetics; V. Size Distributions; VI. Steady State and Fluctuations; VII. Outlook; ACKNOWLEDGMENT S; References; Chapter 2. Fundamentals of Interstitial Collagen Self-Assembly; I. Introduction; II. Fibril-Forming Collagens; III. In Vitro Self-Assembly; IV. Concluding Remarks; References. Chapter 3. Assembly of Collagen Fibrils de Novo from Soluble Precursors: Polymerization and Copolymerization of Procollagen, pN-Collagen, and Mutated CollagensI. Introduction; II. Procollagen Propeptides: Contributions to Solubility and Form; III. Fibril Formation de Novo; IV. Conclusions; ACKNOWLEDGMENTS; References; Chapter 4. Collagen Fibril Assembly, Deposition, and Organization into Tissue-Specific Matrices; I. Introduction; II. Fibril Assembly; III. Fibril Deposition; ACKNOWLEDGMENTS; References. Chapter 5. Heterotypic Type II, IX, and XI Fibrils: Comparison of Vitreous and Cartilage FormsI. Introduction; II. Cartilage Heterotypic Collagen Fibrils: Composition and Organization; III. Fibrillar Collagens; IV. Type IX Collagen; V. Other Fibril-Associated Components; VI. Vitreous Humor Collagens; VII. Summary; ACKNOWLEDGMENTS; References; Chapter 6. Assembly of Type X Collagen by Hypertrophic Chondrocytes; I. Introduction; II. Type X Collagen: Marker for the Maturation of Chondrocytes; III. Type X Collagen Structure; IV. Ultrastructural Assembly of Type X Collagen. V. Temporary Scaffold: Disassembly of the Hypertrophic Cartilage MatrixVI. Calcification of Cartilage; VII. Environmental Modulation of Type X Collagen Synthesis; VIII. Type X Collagen as a Potential Regulatory Molecule in Cartilage; ACKNOWLEDGMENTS; References; Chapter 7. Microfibrillar Collagen Type VI; I. Introduction; II. Protein Assembly and Microfibrillar Model; III. Ultrastructural Evidence for Microfibrils and Heterotypic Interactions; IV. Domain Predictions from the Sequence; V. Recombinant Approaches to Structure and Function; VI. Integrin-Mediated Cell Adhesion. VII. Properties of the GenesVIII. Modulation of Expression and Tissue Distribution; IX. Conclusions; ACKNOWLEDGMENTS; References; Chapter 8. Glycosaminoglycans and Proteoglycans; I. Introduction; II. Proteoglycans; III. Ultrastructural Appearance of Glycosaminoglycans and Proteoglycans in Tissue; IV. In Vitro Interactions of Glycosaminoglycans and Proteoglycans with Extracellular Matrix Compounds; V. Functions of Proteoglycans in the Extracellular Matrix; VI. Concluding Remarks; ACKNOWLEDGMENTS; References; Chapter 9. Elastic Fiber Structure and Assembly; I. Introduction.
Series Title: Biology of extracellular matrix.

Abstract:

Describes the complex and critical process of extracellular matrix (ECM) assembly. This book addresses assembly of many known classes of extracellular matrix macromolecules, discusses higher order  Read more...

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"I liked this book very much, it will play a very useful role in my research and I can heartily recommend its purchase and wide-spread use."--CELL BIOLOGY INTERNATIONAL

 
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