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The genealogy of a gene : patents, HIV/AIDS, and race

Author: Myles W Jackson
Publisher: Cambridge, Massachusetts : MIT Press, 2017.
Series: Transformations : studies in the history of science and technology.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
In this book, the author uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- he links a myriad of diverse topics. The history of CCR5 shows how intellectual  Read more...
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Details

Genre/Form: Patents
Document Type: Book
All Authors / Contributors: Myles W Jackson
ISBN: 9780262533782 0262533782 9780262028660 0262028662
OCLC Number: 1081069134
Description: xii, 336 pages : illustrations, map ; 24 cm.
Contents: The story of the CCR5 gene --
The CCR5 patent(s) --
Gene patenting and the product-of-nature doctrine --
The CCR5 patent and intellectual property law --
The European response to the CCR5 patent --
CCR5 and HIV/AIDS diagnostics and therapeutics --
Race, place, and pathogens --
Race, difference, and genes --
The end of an error?
Series Title: Transformations : studies in the history of science and technology.
Responsibility: Myles W. Jackson.

Abstract:

In this book, the author uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- he links a myriad of diverse topics. The history of CCR5 shows how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. The author describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research. --Publisher description.

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