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GPCRs : from deorphanization to lead structure identification

Author: Henry R Bourne
Publisher: Berlin ; New York : Springer, 2007.
Series: Ernst Schering Foundation symposium proceedings, 2006/2.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

This book offers an insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. Coverage also  Read more...

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Details

Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Henry R Bourne
ISBN: 9783540489818 3540489819
OCLC Number: 77258179
Description: xvii, 267 pages : illustrations, portraits.
Contents: Machine derived contents note: G-Pro eins and GPCRs: From the Beginning --
I.Rf Bourne 1 --
Modeling GPCRs --
A.C. M Paiva Oliveira, E Horn R.P. Bwaoter G. Vriend 23 --
QSAR Modeing of PCR Ligands: --
Methodologies and Examples of Appications --
A. 7'iosha .5X Wang 49 --
Privileged Structures in GPCRs --
R.P. Bwater 75 --
Designing Compond Libraries Targeing GPCRs --
E. Jacoby 93 --
Orphan Seven Transmembrane Receptor Screening --
l Wiggeswrth L.A Wolfe, A. Wise. 105 --
The Role of GPCR Dimerisation/Oligomerisation --
in Receptor Signalling --
G. Miligan, M Canals, JD. Pedian, Ellis, --
I L opezo-Gimenez 145 --
Deophanization of aG-Protein-Coupled Receptors --
. Poi ent , M. Dt x 1. 63 --
Virus-E coded G-Protein-Couped Receptors: --
Constiutively Active (Dys)Regulators of Cell Function --
and Their Potental as Drug Target --
H.F. Vndi, .W. HuNls'if J.P. de Isch, Mf Smiit R. Lens i 7 --
Modulation of GPCR Conformations by Ligands, G-Proteins, --
and Arrestins --
R Prssitr L.A. S r 211 --
High Contenr Screening to Monitor G-Protein-Coupled --
Receptor Internatisation --
R. H eik 229 --
High-Throughput Lead Finding and Optimisation --
for GPR Targets --
A S Swineg, D. C wkil 249 --
Previous Volumes Published in This Series 269.
Series Title: Ernst Schering Foundation symposium proceedings, 2006/2.
Responsibility: H. Bourne [and others], editors.
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