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A guide to human gene therapy

Author: Roland W Herzog; Sergei Zolotukhin
Publisher: New Jersey ; London : World Scientific, ©2010.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Ever since the birth of molecular biology " the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy â" though still in its infancy â" remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle (""vector"") to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the  Read more...
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Genre/Form: Electronic books
Electronic book
Additional Physical Format: Print version:
Guide to human gene therapy.
New Jersey ; London : World Scientific, ©2010
(OCoLC)660502539
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Roland W Herzog; Sergei Zolotukhin
ISBN: 9789814280907 9814280909 9789814280914 9814280917 9781613447796 1613447795 1283143801 9781283143806
OCLC Number: 743217483
Description: 1 online resource (xxvi, 388 pages) : illustrations (some color)
Contents: Non-Viral Vectors (S Sullivan); Adenoviral Vectors (A Baker); Retroviral Vectors and Integration Analysis (C von Kalle); Lentiviral Vectors (T VandenDriessche & M Chuah); Herpes Virus Vectors (J Glorioso); Adeno-Associated Viral (AAV) Vectors (N Muzyczka); Regulatory RNAs (Ribozymes, RNAi and miRNA) (A Lewin); Integrating Vectors (Transposon, Phage Integrase) (M Calos); Gene Correction Strategies/Zinc Fingers (M Porteus); Gene Switches (P Moullier); Gene Therapy for Disorders of the CNS (D Young); Hemoglobinopathies (A Srivastava); Severe Immune Deficiencies (A Aiuti); Hemophilia (R Herzog); Obesity and Diabetes (S Zolotukhin & C Wasserfall); Musculoskeletal Disorders (S Takeda); Cancer Gene Therapy (K Weigel-Van Aiken); Autoimmune Disorders (P Robbins); Lysosomal Storage Diseases (C Mah); Retinal Diseases (B Hauswirth); Pulmonary Diseases (T Flotte); Cardiovascular Diseases (B Byrne).
Responsibility: editors Roland W. Herzog, Sergei Zolotukhin.

Abstract:

Gene therapy remains one of the hottest areas of research in medicine. This book covers topics such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases  Read more...

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