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Hemoglobin : insights into protein structure, function, and evolution

Author: Jay F Storz
Publisher: Oxford, United Kingdom : Oxford University Press, 2019.
Edition/Format:   Print book : English : First editionView all editions and formats
Summary:
The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of  Read more...
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Document Type: Book
All Authors / Contributors: Jay F Storz
ISBN: 9780198810681 0198810687 9780198810698 0198810695
OCLC Number: 1083872578
Description: xii, 237 pages : illustrations (chiefly color) ; 26 cm
Contents: Principles of protein structure --
A study in scarlet: the role of hemoglobin in blood gas transports --
Allosteric theory --
Hemoglobin structure and allosteric mechanism --
Evolution of the vertebrate globin gene family --
Gene duplication and hemoglobin isoform differentiation --
The evolution of novel hemoglobin functions and physiological innovation --
Biochemical adaptation to environmental hypoxia --
Darwin's molecule: evolutionary insights into mechanisms of biochemical adaptation and protein evolution.
Responsibility: Jay F. Storz, Professor, School of Biological Sciences, University of Nebraska.

Abstract:

Provides a synthesis of our current understanding of hemoglobin (Hb) function and evolution, and illustrates how research on this protein has provided more general insights into mechanisms of protein  Read more...

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