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Histopathology of Preclinical Toxicity Studies : Interpretation and Relevance in Drug Safety Evaluation

Author: Peter Greaves
Publisher: London : Academic Press, 2012.
Edition/Format:   Print book : English : 4th edView all editions and formats
Summary:

Describes the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans.  Read more...

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Document Type: Book
All Authors / Contributors: Peter Greaves
ISBN: 9780444538567 0444538569
OCLC Number: 778774101
Description: 1 online resource (886 Seiten : )
Contents: Chapter 1: IntroductionChapter 2: Integumentary System- Skin and subcutaneous tissueChapter 3: Mammary GlandChapter 4: Haemopoietic and Lymphatic Systems- Blood/bone marrow- Lymphoid system- Lymph nodes- Spleen- Thymus- Lymphoreticular neoplasmsChapter 5: Musculoskeletal System- Bone- Joints- Skeletal muscle Chapter 6: Respiratory Tract- Nose, nasal sinuses, nasopharynx and pharynx- Larynx and trachea- Bronchi and lungsChapter 7: Cardiovascular System- Heart and pericardium- Systemic blood vessels- Pulmonary blood vesselsChapter 8: Gastrointestinal tract- Forestomach- Stomach (glandular)- Small intestine- Large intestineChapter 9: Liver and Pancreas- Liver- Bile ducts, biliary system - PancreasChapter 10: Urinary System- Kidney- Urinary bladderChapter 11: Male Genital Tract- Prostate gland- Epididymis- TestisChapter 12: Female Genital Tract- Vagina- Cervix- Uterus- OvaryChapter 13: Endocrine System- Pituitary gland- Adrenal gland- Thyroid gland- Parathyroid glandChapter 14: Nervous System and Special Sense Organs- Brain- Spinal cord, spinal nerve roots, peripheral nerves- Eye- EarSubject index
Responsibility: Peter Greaves.

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"There are several books on the subjects of rodent pathology, toxicologic pathology, and toxicology and several veterinary and toxicologic pathology journals but nothing like this fourth edition of Read more...

 
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