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Human monoclonal antibodies : methods and protocols

Author: Michael Steinitz
Publisher: New York, NY : Humana Press : Springer, [2018] ©2019
Series: Methods in molecular biology (Clifton, N.J.), v. 1904.
Edition/Format:   eBook : Document : English : Second editionView all editions and formats
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Genre/Form: Laboratory Manual
Electronic books
Laboratory manuals
Additional Physical Format: Print version:
Human monoclonal antibodies.
New York, NY : Humana Press : Springer, [2018]
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael Steinitz
ISBN: 9781493989584 1493989588
OCLC Number: 1078787307
Description: 1 online resource (xiv, 483 pages) : illustrations (some color)
Contents: Dedication...Preface...Table of Contents...Contributing Authors...1. Human Monocolonal Antibodies: The Benefits of HumanizationHerman Waldmann2. Cancer Immunotherapy: The Dawn of Antibody CocktailsIlaria Marrocco, Donatella Romaniello, and Yosef Yarden3. IgM Natural Autoantibodies in Physiology and the Treatment of DiseaseMahboobeh Fereidan-Esfahani, Tarek Nayfeh, Arthur Warrington, Charles L. Howe, and Moses Rodriguez4. Monoclonal Antibodies for the Treatment of Melanoma: Present and Future StrategiesMadhuri Bhandaru and Anand Rotte5. An Efficient Method to generate Monoclonal Antibodies from Human B CellsJenna J. Guthmiller, Haley L. Dugan, Karlynn E. Neu, Linda Yu-Ling Lan, and Patrick C. Wilson6. Isolation of Antigen-Specific, antibody-Secreting Cells using a Chip-Based Immunospot ArrayHiroyuki Kishi, Tatsuhiko Ozawa, Hiroshi Hamana, Eiji Kobayashi, and Atsushi Muraguchi7. Purification of Human Monoclonal antibodies and Their FragmentsNicole Ulmer, Sebastian Vigg, Thomas Muller-Spath, and Massimo Morbidelli8. One-Tube Multicolor Flow Cytometry Assay (OTMA) for Comprehensive Immunophenotyping of Peripheral BloodAnna-Jasmina Donaubauer, Paul F. Ruhle, Ina Becker, Rainer Fietkau, Udo S. Gaipl, and Benjamin Frey9. Humanization and Simultaneous Optimization of Monoclonal AntibodyT. Kuramochi, T. Igawa, H. Tsunoda, and K. Hattori10. Antibody Fragments Humanization: Beginning with the End in MindNicolas Aubrey and Philippe Billiald11. Antigen-Specific Human Monoclonal Antibodies from Transgenic MiceSusana Magadan Mompo and Africa Gonzalez-Fernandez12. Refining the Quality of Monoclonal Antibodies: Grafting Unique Peptide-Binding Site in the Fab FrameworkJeremy D. King and John C. Williams13. Basic Procedures for Detection and Cytotoxicity of Chimeric Antigen ReceptorsKeichiro Mihara, Tetsumi Yoshida, and Joyeeta Bhattacharyya14. Rapid Chimerization of AntibodiesKoji Hashimoto, Kohei Kurosawa, Hidetaka Seo, and Kunihiro Ohta15. Phage Display Technology for Human Monoclonal AntibodiesDal Ferro Marco, Rizzo Serena, Rizzo Emanuela, Marano Francesca, Luisis Immacoloata, Tarasiuk Olga, and Daniele Sblattero16. Recombinant Antibody Selections by Combining Phage and Yeast DisplayFortunato Ferrara, Maria Felicia Soluri, and Daniele Sblattero17. Epitope Mapping via Phage Display from Single Gene LibrariesViola Fuhner, Philip Alexander Heine, Kilian Zilkens, Doris Meier, Kristian Daniel Ralph Roth, Gustavo Marcal Schmidt Garcia Moreira, Michael Hust, and Giulio Russo18. A High-Throughput Magnetic Nanoparticle Based Semi-Automated Antibody Phage Display BiopanningAngela Chiew Wen Ch'ng, Azimah Ahmad, Zoltan Konthur, and Theam Soon Lim19. A Binding Potency Assay for Pritumumab and Ecto-Domain Vimentin Ivan Babic, Santosh Kesari, and Mark C. Glossy20. A Method to Detect the Binding of Hyper-Glycosylated Fragment Crystallizable (Fc) Region of Human IgG1 to Glycan ReceptorsPatricia Blundell and Richard Pleass21. A Cell-Based Reporter Assay Measuring the Activation of Fc Gamma Receptors Induced by Therapeutic Monoclonal AntibodiesMichihiko Aoyama, Minoru Tada, and Akiko Ishii-Watabe22. "BIClonals": Production of Bispecific Antibodies in IgG Format in Transiently Transfected Mammalian CellsDana Litvak-Greenfeld, Lilach Vaks, Stav Dror, Limor Nahary, and Itai Benhar23. Production of Stabilized Antibody Fragments in the E. coli Bacterial Cytoplasm and in Transiently-Transfected Mammalian CellsRacheli Birnboim-Perach, Yehudit Grinberg, Lilach Vaks, Limor Nahary, and Itai Benhar
Series Title: Methods in molecular biology (Clifton, N.J.), v. 1904.
Responsibility: edited by Michael Steinitz.

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