skip to content
Covid-19 virus
COVID-19 Resources

Reliable information about the coronavirus (COVID-19) is available from the World Health Organization (current situation, international travel). Numerous and frequently-updated resource results are available from this WorldCat.org search. OCLC’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus issues in their communities.

Image provided by: CDC/ Alissa Eckert, MS; Dan Higgins, MAM
Humoral Immunity in Children with Down Syndrome: relevance to respiratory disease Preview this item
ClosePreview this item
Checking...

Humoral Immunity in Children with Down Syndrome: relevance to respiratory disease

Author: Ruud Verstegen
Publisher: Erasmus University Rotterdam 2015-01-28
Edition/Format: Book Book : English
Summary:
markdownabstract__Abstract__ Down syndrome is the most common cause of developmental delay in humans. In The Netherlands, each year approximately 250 children with Down syndrome are born. Individuals with Down syndrome suffer from increased incidences of respiratory tract infections, autoimmune disease and haematological malignancies. This triad is reminiscent of immunodefi ciencies and has led to the hypothesis of  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Find a copy online

Links to this item

Find a copy in the library

We were unable to get information about libraries that hold this item.

Details

Document Type: Book
All Authors / Contributors: Ruud Verstegen
ISBN: 978-94-91811-05-0
Language Note: English
Unique Identifier: 6893682357
Awards:

Abstract:

markdownabstract__Abstract__ Down syndrome is the most common cause of developmental delay in humans. In The Netherlands, each year approximately 250 children with Down syndrome are born. Individuals with Down syndrome suffer from increased incidences of respiratory tract infections, autoimmune disease and haematological malignancies. This triad is reminiscent of immunodefi ciencies and has led to the hypothesis of an altered immune system in Down syndrome. The high incidence of respiratory tract infections is an important clinical problem and is suggestive of an immune defect. Therefore, the work described in this thesis was focused on the nature of these respiratory tract infections and dissection of adaptive immunity, especially regarding humoral immunity.

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


\n\n

Primary Entity<\/h3>\n
<http:\/\/www.worldcat.org\/oclc\/6893682357<\/a>> # Humoral Immunity in Children with Down Syndrome: relevance to respiratory disease<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Book<\/a>, schema:CreativeWork<\/a> ;\u00A0\u00A0\u00A0\nlibrary:oclcnum<\/a> \"6893682357<\/span>\" ;\u00A0\u00A0\u00A0\nrdfs:comment<\/a> \"949 $l doctoralthesis<\/span>\" ;\u00A0\u00A0\u00A0\nschema:creator<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/3985290081#Person\/verstegen_ruud<\/a>> ; # Ruud Verstegen<\/span>\n\u00A0\u00A0\u00A0\nschema:datePublished<\/a> \"2015\/01\/28<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"markdownabstract__Abstract__ Down syndrome is the most common cause of developmental delay in humans. In The Netherlands, each year approximately 250 children with Down syndrome are born. Individuals with Down syndrome suffer from increased incidences of respiratory tract infections, autoimmune disease and haematological malignancies. This triad is reminiscent of immunodefi ciencies and has led to the hypothesis of an altered immune system in Down syndrome. The high incidence of respiratory tract infections is an important clinical problem and is suggestive of an immune defect. Therefore, the work described in this thesis was focused on the nature of these respiratory tract infections and dissection of adaptive immunity, especially regarding humoral immunity.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:exampleOfWork<\/a> <http:\/\/worldcat.org\/entity\/work\/id\/3985290081<\/a>> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Humoral Immunity in Children with Down Syndrome: relevance to respiratory disease<\/span>\" ;\u00A0\u00A0\u00A0\nschema:productID<\/a> \"6893682357<\/span>\" ;\u00A0\u00A0\u00A0\nschema:publication<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/#PublicationEvent\/erasmus_university_rotterdam2015_01_28<\/a>> ;\u00A0\u00A0\u00A0\nschema:publisher<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/3985290081#Agent\/erasmus_university_rotterdam<\/a>> ; # Erasmus University Rotterdam<\/span>\n\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/hdl.handle.net\/1765\/77471<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/worldcat.org\/isbn\/978-94-91811-05-0<\/a>> ;\u00A0\u00A0\u00A0\nwdrs:describedby<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/6893682357<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Related Entities<\/h3>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/3985290081#Agent\/erasmus_university_rotterdam<\/a>> # Erasmus University Rotterdam<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:Agent<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Erasmus University Rotterdam<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/3985290081#Person\/verstegen_ruud<\/a>> # Ruud Verstegen<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Ruud Verstegen<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/hdl.handle.net\/1765\/77471<\/a>>\u00A0\u00A0\u00A0\nrdfs:comment<\/a> \"NARCIS<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/978-94-91811-05-0<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"978-94-91811-05-0<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/#PublicationEvent\/erasmus_university_rotterdam2015_01_28<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:PublicationEvent<\/a> ;\u00A0\u00A0\u00A0\nschema:organizer<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/3985290081#Agent\/erasmus_university_rotterdam<\/a>> ; # Erasmus University Rotterdam<\/span>\n\u00A0\u00A0\u00A0\nschema:startDate<\/a> \"2015-01-28<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/6893682357<\/a>>\u00A0\u00A0\u00A0\u00A0a \ngenont:InformationResource<\/a>, genont:ContentTypeGenericResource<\/a> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/www.worldcat.org\/oclc\/6893682357<\/a>> ; # Humoral Immunity in Children with Down Syndrome: relevance to respiratory disease<\/span>\n\u00A0\u00A0\u00A0\nschema:dateModified<\/a> \"2019-10-09<\/span>\" ;\u00A0\u00A0\u00A0\nvoid:inDataset<\/a> <http:\/\/purl.oclc.org\/dataset\/narcis<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Content-negotiable representations<\/p>\n