skip to content
Covid-19 virus
COVID-19 Resources

Reliable information about the coronavirus (COVID-19) is available from the World Health Organization (current situation, international travel). Numerous and frequently-updated resource results are available from this WorldCat.org search. OCLC’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus issues in their communities.

Image provided by: CDC/ Alissa Eckert, MS; Dan Higgins, MAM
Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus Preview this item
ClosePreview this item
Checking...

Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus

Author: Christopher Armoskus
Publisher: [Long Beach, California] : California State University, Long Beach, 2013.
Dissertation: M.S. California State University, Long Beach 2013
Series: California State University, Long Beach.; Master's thesis collection, Dept. of Biological Sciences.
Edition/Format:   Thesis/dissertation : Document : Thesis/dissertation   Computer File : English
Summary:
Abstract: In both mice and humans, males and females exhibit differences in behavior and response to neurological and psychological diseases that are linked to the cortex and hippocampus. The perinatal exposure of males to testosterone secreted by the testes creates alterations in neural structures and behaviors that can persist throughout their lives; however, the molecular mechanisms that underlie the actions of  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Academic theses
Material Type: Document, Thesis/dissertation, Internet resource
Document Type: Book, Computer File, Internet Resource
All Authors / Contributors: Christopher Armoskus
ISBN: 9781303766329 1303766329
OCLC Number: 1020289013
Description: ix, 93 leaves : illustrations, charts
Series Title: California State University, Long Beach.; Master's thesis collection, Dept. of Biological Sciences.
Responsibility: by Christopher Armoskus.

Abstract:

Abstract: In both mice and humans, males and females exhibit differences in behavior and response to neurological and psychological diseases that are linked to the cortex and hippocampus. The perinatal exposure of males to testosterone secreted by the testes creates alterations in neural structures and behaviors that can persist throughout their lives; however, the molecular mechanisms that underlie the actions of sex steroids to produce these lasting changes are still unclear. Given that regulation of gene expression is a primary mechanism whereby sex steroids exert changes to an organism, I sought to identify genes expressed at different levels between the sexes in the cortex and hippocampus and to determine the effect of testosterone on expression of these genes. Using gene expression microarrays and RT-qPCR, I identified genes that are differentially expressed between the sexes in the neonatal mouse cortex and hippocampus; however, whether perinatal testosterone is regulating these differences remains unclear.

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


\n\n

Primary Entity<\/h3>\n
<http:\/\/www.worldcat.org\/oclc\/1020289013<\/a>> # Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Book<\/a>, schema:CreativeWork<\/a>, schema:MediaObject<\/a>, bgn:Thesis<\/a> ;\u00A0\u00A0\u00A0\nbgn:inSupportOf<\/a> \"\" ;\u00A0\u00A0\u00A0\nlibrary:oclcnum<\/a> \"1020289013<\/span>\" ;\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/id.loc.gov\/vocabulary\/countries\/cau<\/a>> ;\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Place\/long_beach_california<\/a>> ; # Long Beach, California<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/mice_development<\/a>> ; # Mice--Development<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/steroids_genetic_aspects<\/a>> ; # Steroids--Genetic aspects<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/sexual_dimorphism_animals<\/a>> ; # Sexual dimorphism (Animals)<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/gene_expression<\/a>> ; # Gene expression<\/span>\n\u00A0\u00A0\u00A0\nschema:creator<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Person\/armoskus_christopher<\/a>> ; # Christopher Armoskus<\/span>\n\u00A0\u00A0\u00A0\nschema:datePublished<\/a> \"2013<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Abstract: In both mice and humans, males and females exhibit differences in behavior and response to neurological and psychological diseases that are linked to the cortex and hippocampus. The perinatal exposure of males to testosterone secreted by the testes creates alterations in neural structures and behaviors that can persist throughout their lives; however, the molecular mechanisms that underlie the actions of sex steroids to produce these lasting changes are still unclear. Given that regulation of gene expression is a primary mechanism whereby sex steroids exert changes to an organism, I sought to identify genes expressed at different levels between the sexes in the cortex and hippocampus and to determine the effect of testosterone on expression of these genes. Using gene expression microarrays and RT-qPCR, I identified genes that are differentially expressed between the sexes in the neonatal mouse cortex and hippocampus; however, whether perinatal testosterone is regulating these differences remains unclear.<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:exampleOfWork<\/a> <http:\/\/worldcat.org\/entity\/work\/id\/4732552138<\/a>> ;\u00A0\u00A0\u00A0\nschema:genre<\/a> \"Academic theses<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:inLanguage<\/a> \"en<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isPartOf<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Series\/master_s_thesis_collection_dept_of_biological_sciences<\/a>> ; # Master\'s thesis collection, Dept. of Biological Sciences.<\/span>\n\u00A0\u00A0\u00A0\nschema:name<\/a> \"Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:productID<\/a> \"1020289013<\/span>\" ;\u00A0\u00A0\u00A0\nschema:publication<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/1020289013#PublicationEvent\/long_beach_california_california_state_university_long_beach_2013<\/a>> ;\u00A0\u00A0\u00A0\nschema:publisher<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Agent\/california_state_university_long_beach<\/a>> ; # California State University, Long Beach<\/span>\n\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/search.proquest.com\/docview\/1508568889?accountid=10351<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/worldcat.org\/isbn\/9781303766329<\/a>> ;\u00A0\u00A0\u00A0\nwdrs:describedby<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/1020289013<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Related Entities<\/h3>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Agent\/california_state_university_long_beach<\/a>> # California State University, Long Beach<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:Agent<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"California State University, Long Beach<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Organization\/california_state_university_long_beach<\/a>> # California State University, Long Beach.<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Organization<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"California State University, Long Beach.<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Person\/armoskus_christopher<\/a>> # Christopher Armoskus<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Armoskus<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Christopher<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Christopher Armoskus<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Place\/long_beach_california<\/a>> # Long Beach, California<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Long Beach, California<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Series\/master_s_thesis_collection_dept_of_biological_sciences<\/a>> # Master\'s thesis collection, Dept. of Biological Sciences.<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:PublicationSeries<\/a> ;\u00A0\u00A0\u00A0\nschema:creator<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Organization\/california_state_university_long_beach<\/a>> ; # California State University, Long Beach.<\/span>\n\u00A0\u00A0\u00A0\nschema:hasPart<\/a> <http:\/\/www.worldcat.org\/oclc\/1020289013<\/a>> ; # Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus<\/span>\n\u00A0\u00A0\u00A0\nschema:name<\/a> \"Master\'s thesis collection, Dept. of Biological Sciences.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"[Master\'s thesis collection, Dept. of Biological Sciences]<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/gene_expression<\/a>> # Gene expression<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Gene expression<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/mice_development<\/a>> # Mice--Development<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Mice--Development<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/sexual_dimorphism_animals<\/a>> # Sexual dimorphism (Animals)<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Sexual dimorphism (Animals)<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Topic\/steroids_genetic_aspects<\/a>> # Steroids--Genetic aspects<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Steroids--Genetic aspects<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.loc.gov\/vocabulary\/countries\/cau<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\ndcterms:identifier<\/a> \"cau<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/9781303766329<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"1303766329<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"9781303766329<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/1020289013<\/a>>\u00A0\u00A0\u00A0\u00A0a \ngenont:InformationResource<\/a>, genont:ContentTypeGenericResource<\/a> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/www.worldcat.org\/oclc\/1020289013<\/a>> ; # Identification and characterization of sexually dimorphic genes in the developing mouse cortex and hippocampus<\/span>\n\u00A0\u00A0\u00A0\nschema:dateModified<\/a> \"2019-09-28<\/span>\" ;\u00A0\u00A0\u00A0\nvoid:inDataset<\/a> <http:\/\/purl.oclc.org\/dataset\/WorldCat<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/1020289013#PublicationEvent\/long_beach_california_california_state_university_long_beach_2013<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:PublicationEvent<\/a> ;\u00A0\u00A0\u00A0\nschema:location<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Place\/long_beach_california<\/a>> ; # Long Beach, California<\/span>\n\u00A0\u00A0\u00A0\nschema:organizer<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/4732552138#Agent\/california_state_university_long_beach<\/a>> ; # California State University, Long Beach<\/span>\n\u00A0\u00A0\u00A0\nschema:startDate<\/a> \"2013<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Content-negotiable representations<\/p>\n