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Implementing and evaluating genomic screening programs in health care systems : proceedings of a workshop

Author: Siobhan Addie; Meredith Hackmann; Theresa M Wizemann; Sarah H Beachy; National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Genomics and Precision Health,
Publisher: Washington, DC : The National Academies Press, 2018.
Edition/Format:   eBook : Document : Conference publication : EnglishView all editions and formats
Summary:
Genomic applications are being integrated into a broad range of clinical and research activities at health care systems across the United States. This trend can be attributed to a variety of factors, including the declining cost of genome sequencing and the potential for improving health outcomes and cutting the costs of care. The goals of these genomics-based programs may be to identify individuals with clinically  Read more...
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Genre/Form: Electronic books
Congress
Conference papers and proceedings
Congresses
Additional Physical Format: Print version:
Addie, Siobhan.
Implementing and evaluating genomic screening programs in health care systems.
Washington, DC : National Academies Press, [2018]
(OCoLC)1030602523
Material Type: Conference publication, Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Siobhan Addie; Meredith Hackmann; Theresa M Wizemann; Sarah H Beachy; National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Genomics and Precision Health,
ISBN: 9780309473446 0309473446 9780309473422 030947342X
OCLC Number: 1037018888
Notes: "Proceedings of a workshop"--Cover.
Description: 1 online resource (1 PDF file (xx, 130 pages)) : illustrations
Contents: Introduction --
Evidence considerations for integrating genomics-based programs into health care systems --
Financial considerations for implementing genomics-based screening programs --
Exploring approaches to optimize data sharing among early implementers of genomics-based programs --
Understanding participant needs and preferences and improving diversity and equity --
Improving health through the integration of genomics-based programs: potential next steps.
Responsibility: Siobhan Addie, Meredith Hackmann, Theresa Wizemann, and Sarah Beachy, rapporteurs ; Roundtable on Genomics and Precision Health, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine.

Abstract:

Genomic applications are being integrated into a broad range of clinical and research activities at health care systems across the United States. This trend can be attributed to a variety of factors, including the declining cost of genome sequencing and the potential for improving health outcomes and cutting the costs of care. The goals of these genomics-based programs may be to identify individuals with clinically actionable variants as a way of preventing disease, providing diagnoses for patients with rare diseases, and advancing research on genetic contributions to health and disease. Of particular interest are genomics- based screening programs, which will, in this publication, be clinical screening programs that examine genes or variants in unselected populations in order to identify individuals who are at an increased risk for a particular health concern (e.g., diseases, adverse drug outcomes) and who might benefit from clinical interventions. On November 1, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop to explore the challenges and opportunities associated with integrating genomics-based screening programs into health care systems. This workshop was developed as a way to explore the challenges and opportunities associated with integrating genomics-based programs in health care systems in the areas of evidence collection, sustainability, data sharing, infrastructure, and equity of access. This publication summarizes the presentations and discussions from the workshop.

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Primary Entity<\/h3>\n
<http:\/\/www.worldcat.org\/oclc\/1037018888<\/a>> # Implementing and evaluating genomic screening programs in health care systems : proceedings of a workshop<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Book<\/a>, schema:MediaObject<\/a>, schema:CreativeWork<\/a> ;\u00A0\u00A0\u00A0\nlibrary:oclcnum<\/a> \"1037018888<\/span>\" ;\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/id.loc.gov\/vocabulary\/countries\/dcu<\/a>> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_disorders_united_states<\/a>> ; # Genetic disorders--United States<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/medical_care_united_states<\/a>> ; # Medical care--United States<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_disorders<\/a>> ; # Genetic disorders<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/medical_care<\/a>> ; # Medical care<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/mass_screening<\/a>> ; # Mass Screening<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/human_chromosome_abnormalities_diagnosis<\/a>> ; # Human chromosome abnormalities--Diagnosis<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genomics<\/a>> ; # Genomics<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_testing<\/a>> ; # Genetic Testing<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/science_life_sciences_biochemistry<\/a>> ; # SCIENCE--Life Sciences--Biochemistry<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/dewey.info\/class\/572.865\/e23\/<\/a>> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genomics_united_states<\/a>> ; # Genomics--United States<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Place\/united_states<\/a>> ; # United States.<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/human_chromosome_abnormalities_diagnosis_united_states<\/a>> ; # Human chromosome abnormalities--Diagnosis--United States<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_screening_united_states<\/a>> ; # Genetic screening--United States<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_predisposition_to_disease<\/a>> ; # Genetic Predisposition to Disease<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_screening<\/a>> ; # Genetic screening<\/span>\n\u00A0\u00A0\u00A0\nschema:bookFormat<\/a> schema:EBook<\/a> ;\u00A0\u00A0\u00A0\nschema:contributor<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Person\/wizemann_theresa_m<\/a>> ; # Theresa M. 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The goals of these genomics-based programs may be to identify individuals with clinically actionable variants as a way of preventing disease, providing diagnoses for patients with rare diseases, and advancing research on genetic contributions to health and disease. Of particular interest are genomics- based screening programs, which will, in this publication, be clinical screening programs that examine genes or variants in unselected populations in order to identify individuals who are at an increased risk for a particular health concern (e.g., diseases, adverse drug outcomes) and who might benefit from clinical interventions. On November 1, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop to explore the challenges and opportunities associated with integrating genomics-based screening programs into health care systems. This workshop was developed as a way to explore the challenges and opportunities associated with integrating genomics-based programs in health care systems in the areas of evidence collection, sustainability, data sharing, infrastructure, and equity of access. 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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Meeting\/implementing_and_evaluating_genomic_screening_programs_in_health_care_systems_workshop_2017_washington_d_c<\/a>> # Implementing and Evaluating Genomic Screening Programs in Health Care Systems (Workshop) (2017 : Washington, D.C.)<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:Meeting<\/a>, schema:Event<\/a> ;\u00A0\u00A0\u00A0\nschema:location<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Place\/washington_d_c<\/a>> ; # Washington, D.C.)<\/span>\n\u00A0\u00A0\u00A0\nschema:name<\/a> \"Implementing and Evaluating Genomic Screening Programs in Health Care Systems (Workshop) (2017 : Washington, D.C.)<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Organization\/national_academies_of_sciences_engineering_and_medicine_u_s_roundtable_on_genomics_and_precision_health<\/a>> # National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Genomics and Precision Health,<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Organization<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Genomics and Precision Health,<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Person\/addie_siobhan<\/a>> # Siobhan Addie<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Addie<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Siobhan<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Siobhan Addie<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Person\/beachy_sarah_h<\/a>> # Sarah H. Beachy<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Beachy<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Sarah H.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Sarah H. Beachy<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Person\/hackmann_meredith<\/a>> # Meredith Hackmann<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Hackmann<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Meredith<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Meredith Hackmann<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Person\/wizemann_theresa_m<\/a>> # Theresa M. Wizemann<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Wizemann<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Theresa M.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Theresa M. Wizemann<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Place\/united_states<\/a>> # United States.<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"United States.<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Place\/washington_d_c<\/a>> # Washington, D.C.)<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Washington, D.C.)<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_disorders<\/a>> # Genetic disorders<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic disorders<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_disorders_united_states<\/a>> # Genetic disorders--United States<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic disorders--United States<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_predisposition_to_disease<\/a>> # Genetic Predisposition to Disease<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic Predisposition to Disease<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_screening<\/a>> # Genetic screening<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic screening<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_screening_united_states<\/a>> # Genetic screening--United States<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic screening--United States<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genetic_testing<\/a>> # Genetic Testing<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic Testing<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genomics<\/a>> # Genomics<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genomics<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/genomics_united_states<\/a>> # Genomics--United States<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genomics--United States<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/human_chromosome_abnormalities_diagnosis<\/a>> # Human chromosome abnormalities--Diagnosis<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Human chromosome abnormalities--Diagnosis<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/human_chromosome_abnormalities_diagnosis_united_states<\/a>> # Human chromosome abnormalities--Diagnosis--United States<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Human chromosome abnormalities--Diagnosis--United States<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/mass_screening<\/a>> # Mass Screening<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Mass Screening<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/medical_care<\/a>> # Medical care<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Medical care<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/5173655494#Topic\/medical_care_united_states<\/a>> # Medical care--United States<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Medical care--United States<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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<http:\/\/www.worldcat.org\/title\/-\/oclc\/1037018888<\/a>>\u00A0\u00A0\u00A0\u00A0a \ngenont:InformationResource<\/a>, genont:ContentTypeGenericResource<\/a> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/www.worldcat.org\/oclc\/1037018888<\/a>> ; # Implementing and evaluating genomic screening programs in health care systems : proceedings of a workshop<\/span>\n\u00A0\u00A0\u00A0\nschema:dateModified<\/a> \"2020-03-18<\/span>\" ;\u00A0\u00A0\u00A0\nvoid:inDataset<\/a> <http:\/\/purl.oclc.org\/dataset\/WorldCat<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Content-negotiable representations<\/p>\n