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Inhalation aerosols : physical and biological basis for therapy

Author: Anthony J Hickey; Heidi M Mansour
Publisher: New York, NY : CRC Press, [2019]
Series: Lung biology in health and disease, 1.
Edition/Format:   eBook : Document : English : Third editionView all editions and formats
Summary:
Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Inhalation aerosols.
New York, NY : CRC Press, [2019]
(DLC) 2018043533
(OCoLC)1052505558
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Anthony J Hickey; Heidi M Mansour
ISBN: 9781315159768 1315159767 9781351660518 1351660519 9781351660525 1351660527
OCLC Number: 1091894652
Description: 1 online resource (pages)
Contents: 0. IntroductionAnthony J. Hickey and Heidi M. MansourSection 1 FundamentalsPhysicochemical Properties of Respiratory Particles and FormulationsB. ShekunovParticle Deposition in the Respiratory Tract and the Effect of Respiratory DiseaseDr. William BennettMathematical Modeling of Inhaled Therapeutic Aerosol Deposition in the Respiratory TractJeffry Schroeter, Bahman Asgharian, and Julia KimbellLung transporters & absorption mechanisms in the lungs. Mohammed Ali Selo,, Hassan H. A. Al-Alak, Carsten EhrhardtBioavailability of inhaled compounds. L. Garcia-Contreras3D models as tools for inhaled drug development. Sally-Ann Cryan, Jennifer Lorigan, Cian O'LearyOverview of the delivery technologies for inhalation aerosols Daniel F. Moraga-Espinoza, Ashlee D. Brunaugh, Silvia Ferrati, Lara A. Heersema, Matthew J. Herpin, Patricia P. Martins, Hairui Zhang, Hugh D. C. Smyth Section 2 Applications, Influence of Lung Disease Pathophysiology on Aerosol Deposition, Inhaler Device Technique in Respiratory Disease, & Clinical Outcomes in Drug Performance Assessment Neonatal & Pediatric Inhalation Drug DeliveryAriel Berlinski AsthmaOmar UsmaniDrug Delivery in Pulmonary AspergillosisSawittree Sahakijpijarn, Jay I. Peters, Robert O. Williams IIILung Cancer Inhalation TherapeuticsRajiv DhandInhaled Therapeutics in Chronic Obstructive Pulmonary DiseaseTejas Sinha, Paul DeJulio and Philip Diaz Cystic fibrosis infection & Biofilm BustersJennifer Fiegel and Sachin GharseCURRENT AND FUTURE CFTR Therapeutics-Marne C. Hagemeijer, Gimano D. Amatngalim and Jeffrey M. Beekman Innate and Adaptive Barrier Properties of Airway MucusAlison Schaefer, Samuel K. LaiNon-tuberculous mycobacteria (NTM)M. Ghadiri, P. M. Young, and D. TrainiInhalational Therapies for Non-CF Bronchiectasis Ashvini Damodaran, Dustin R. Fraidenburg, and Israel RubinsteinPulmonary Fibrosis, Priya Muralidharan, Dr. Don Hayes, Jr, and Dr. Heidi M. MansourTherapeutics in Pulmonary HypertensionMaria F. Acosta, Don Hayes, Jr., Jeffrey R. Fineman, Jason X.-J. Yuan, Stephen M. Black, and Heidi M. MansourRespiratory distress syndrome, Heidi M. Mansour, Debra Droopad, and Julie G. LedfordSurfactant Aerosol Therapy for nRDS and ARDSDonovan B. YeatesFundamentals in Nasal Drug Delivery Zachary Warnken, Yu jin Kim, Heidi M. Mansour, Robert O. Williams III, Hugh D.C. SmythInhaled therapeutics against TB: the promise of pulmonary treatment and prevention strategies in the clinicDominique N; Kunda, Nitesh K. Miller, Elliott K.; Muttil, PavanSection 3 Integrated strategies (reflecting combined elements from chapters 8-23): Inhaled medication: factors that affect lung depositionJoy ConwayA Critical Perspective on Future developments based on the knowledge we have nowTania F. Bahamondez-Canas, Jasmim Leal, Hugh D.C. Smyth 26. Ensuring Effectiveness and Reproducibility of Inhaled Drug Treatment Anthony J Hickey27. ConclusionA.J. Hickey, and H.M. Mansour
Series Title: Lung biology in health and disease, 1.
Responsibility: edited by Anthony J. Hickey, Heidi M. Mansour.

Abstract:

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

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