skip to content
Inhibitors of molecular chaperones as therapeutic agents Preview this item
ClosePreview this item
Checking...

Inhibitors of molecular chaperones as therapeutic agents

Author: Timothy D Machajewski; Zhenhai Gao
Publisher: Cambridge : RSC Publishing, 2014.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research.

Rating:

(not yet rated) 0 with reviews - Be the first.

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Timothy D Machajewski; Zhenhai Gao
ISBN: 9781849739689 1849739684
OCLC Number: 1100880758
Description: 1 online resource : illustrations
Contents: Section I Structure and Function: Conformational Dynamics, Structure and Functional Interactions of Hsp90 Chaperones; Structural Basis of Hsp90 Function; Structure and Function of Hsp70 - TBD; Exploiting the Dependency of Cancer Cells on Molecular Chaperones; Section II Small Molecule Inhibitors; Discovery of BIIB028; Discovery of STA-9090; Discovery of Serenex Hsp90 Inhibitor; Discovery of NVP-AUY922; Discovery of NVP-HSP990; Inhibitors of Hsp90 C-Terminal Domain; Hsp70 Inhibitors; Section III Clinical Perspectives; Clinical Development of Hsp90 Inhibitors as Anti-Cancer Agents; Hsp90 as a Potential Anti-Malarial Agent; Biomarker Development and Indication Selection; Other Disease Indications
Responsibility: edited by Timothy D. Machajewski and Zhenhai Gao.

Reviews

Editorial reviews

Publisher Synopsis

Since the discovery in the mid-1990s that geldanamycin, a benzo- quinone ansamcin, acts as an inhibitor of heat shock protein 90 (Hsp90), research in this area has boomed. Whilst several topics Read more...

 
User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


\n\n

Primary Entity<\/h3>\n
<http:\/\/www.worldcat.org\/oclc\/1100880758<\/a>> # Inhibitors of molecular chaperones as therapeutic agents<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Book<\/a>, schema:CreativeWork<\/a>, schema:MediaObject<\/a> ;\u00A0\u00A0\u00A0\nlibrary:oclcnum<\/a> \"1100880758<\/span>\" ;\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/id.loc.gov\/vocabulary\/countries\/enk<\/a>> ;\u00A0\u00A0\u00A0\nschema:bookFormat<\/a> schema:EBook<\/a> ;\u00A0\u00A0\u00A0\nschema:datePublished<\/a> \"2014<\/span>\" ;\u00A0\u00A0\u00A0\nschema:editor<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/1779745974#Person\/machajewski_timothy_d<\/a>> ; # Timothy D. Machajewski<\/span>\n\u00A0\u00A0\u00A0\nschema:editor<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/1779745974#Person\/gao_zhenhai<\/a>> ; # Zhenhai Gao<\/span>\n\u00A0\u00A0\u00A0\nschema:exampleOfWork<\/a> <http:\/\/worldcat.org\/entity\/work\/id\/1779745974<\/a>> ;\u00A0\u00A0\u00A0\nschema:inLanguage<\/a> \"en<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Inhibitors of molecular chaperones as therapeutic agents<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:productID<\/a> \"1100880758<\/span>\" ;\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/www.vlebooks.com\/vleweb\/product\/openreader?id=none&isbn=9781849739689<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/worldcat.org\/isbn\/9781849739689<\/a>> ;\u00A0\u00A0\u00A0\nwdrs:describedby<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/1100880758<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Related Entities<\/h3>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/1779745974#Person\/gao_zhenhai<\/a>> # Zhenhai Gao<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Gao<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Zhenhai<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Zhenhai Gao<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/1779745974#Person\/machajewski_timothy_d<\/a>> # Timothy D. Machajewski<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Machajewski<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Timothy D.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Timothy D. Machajewski<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.loc.gov\/vocabulary\/countries\/enk<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\ndcterms:identifier<\/a> \"enk<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/9781849739689<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"1849739684<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"9781849739689<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n