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Inhibitors of molecular chaperones as therapeutic agents

Author: Timothy D Machajewski; Zhenhai Gao; David P Rotella
Publisher: [Cambridge] : Royal Society of Chemistry, 2013.
Series: RSC drug discovery series, v. 37.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense interest in the chaperones as a molecular target. Filling a significant gap in the market by providing a detailed comparison of discovery programs across the industry, this  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Timothy D Machajewski; Zhenhai Gao; David P Rotella
ISBN: 9781849739689 1849739684 9781849736664 1849736669
OCLC Number: 863484701
Language Note: English.
Description: 1 online resource.
Contents: _s_h_o_w_7_; _s_h_o_w_247_; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; fig1; _s_h_o_w_13_; _s_h_o_w_20_; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig2; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig3; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig4; fig5; fig5; fig5; fig5; fig5; fig5; fig5; fig5. Fig5fig5; fig5; fig5; fig5; fig5; fig5; fig5; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig6; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig7; fig8; fig8; fig8; fig8; fig8; fig8; fig8; fig8; fig8; fig8; fig9; fig9; fig9; fig9; fig9; fig9; fig9; fig9; fig10; fig10; fig10; fig10; fig10; fig10; fig10; fig10; fig11; fig11; fig11; fig11; fig11; fig11; fig11; fig11; fig12; fig12; fig12; fig12; fig12; fig12; fig13; fig13; fig13; fig13; fig13; fig13; sch1; sch1; sch1; sch1; sch2; sch2; sch2; sch2; sch3; sch3; sch4; sch4; sch5; sch5; sch6; sch6; sch7. Sch7sch8; sch8; sch9; sch9; sch10; sch10; sch11; sch11; sch12; sch12; sch13; sch13; fig14; fig14; fig14; fig14; fig15; fig15; fig15; fig15; fig16; fig16; fig16; fig16; fig17; fig17; fig17; fig17; fig18; fig18; fig18; fig18; fig19; fig19; fig20; fig20; fig21; fig21; fig22; fig22; fig23; fig23; fig24; fig24; fig25; fig25; fig26; fig26; fig27; fig27; fig28; fig28; fig29; fig29; fig30; fig30; fig31; fig31; fig32; fig32; fig33; fig33; fig34; fig34; fig35; fig35; fig36; fig36; _s_h_o_w_308_; _s_h_o_w_351_; fig3a; fig3a; fig3b; fig3b.
Series Title: RSC drug discovery series, v. 37.
Responsibility: [edited by] Timothy D. Machajewski, Zhenhai Gao, David Rotella.

Abstract:

This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research.  Read more...

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"...this 422- page volume adds greatly to the discussion by reporting many of the more recent advances in targeting Hsp90, whilst including an elegant overview of the advances in Hsp70 research, an Read more...

 
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