Integrating clinical research into epidemic response : the Ebola experience (Book, 2017) [WorldCat.org]
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Integrating clinical research into epidemic response : the Ebola experience

Author: Gerald KeuschKeith P W J McAdamPatricia A CuffMichelle MancherEmily R BustaAll authors
Publisher: Wasington, DC : National Academies Press 2017. ©2017
Series: Report (National Academies of Sciences, Engineering, and Medicine (U.S.))
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"The 2014-2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West  Read more...
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Additional Physical Format: Online version :
National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Clinical Trials During the 2014--2015 Ebola Outbreak.
Integrating clinical research into epidemic response.
Washington, D.C. : National Academies Press, [2017]
(OCoLC)992788402
Document Type: Book
All Authors / Contributors: Gerald Keusch; Keith P W J McAdam; Patricia A Cuff; Michelle Mancher; Emily R Busta; National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Clinical Trials During the 2014-2015 Ebola Outbreak.
ISBN: 9780309457767 0309457769
OCLC Number: 989056837
Description: xxvi, 316 pages : color illustrations ; 23 cm
Contents: Introduction --
Conducting clinical research during an epidemic --
Assessment of therapeutic trials --
Assessment of vaccine trials --
Strengthening capacity for response and research --
Engaging communities in research and response --
Facilitating international coordination and collaboration --
Appendix A. Study approach and methods --
Appendix B. Clinical trial designs --
Appendix C. Ethical principles for research with human subjects --
Appendix D. Biographical sketches of committee members and staff.
Series Title: Report (National Academies of Sciences, Engineering, and Medicine (U.S.))
Responsibility: Gerald Keusch, Keith McAdam, Patricia A. Cuff, Michelle Mancher, and Emily R. Busta, editors ; Committee on Clinical Trials During the 2014--2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division, a report of the National Academies of Sciences, Engineering, Medicine.

Abstract:

"The 2014-2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014-2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014-2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events"--Publisher's description.

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