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Introduction to Evolutionary Genomics.

Author: Naruya Saitou
Publisher: New York : Springer Feb. 2014.
Series: Computational Biology Ser., 17.
Edition/Format:   eBook : Document : English
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Naruya Saitou
ISBN: 9781447153030 1447153030
OCLC Number: 876282479
Target Audience: Scholarly & Professional
Description: 1 online resource (495 pages) illustrations.
Contents: Intro; Preface; Necessity of Evolutionary Studies; What Is Evolution?; What Is a Genome?; Vitalism Versus Mechanism; Everything Is History; Genome as a Republic of Genes; Structure of This Book; Acknowledgments; References; Contents; Part I: Basic Processes of Genome Evolution; 1: Basic Metabolism Surrounding DNAs; 1.1 Central Dogma of Molecular Biology; 1.2 DNA Replication; 1.2.1 Chemical Nature of DNA Molecules; 1.2.2 DNA Replication Systems; 1.3 Transcription; 1.3.1 RNA; 1.3.2 Messenger RNA (mRNA); 1.3.3 Transcription Machinery and Splicing; 1.3.4 RNA Editing 1.4 Translation and Genetic Codes1.4.1 Transfer RNA (tRNA); 1.4.2 Genetic Codes; 1.4.3 Ribosome and Translation; 1.5 Proteins; 1.5.1 Amino Acids; 1.5.2 Four Strata of the Protein Structure; 1.5.3 Protein Diversity; 1.5.4 Protein Domains and Motifs; 1.6 Genes; 1.6.1 Protein Coding Genes; 1.6.2 Chromosomes; References; 2: Mutation; 2.1 Classification of Mutations; 2.1.1 What Is Mutation?; 2.1.2 Temporal Unit of Mutation; 2.1.3 Mutations Affecting Small Regions of DNA Sequences; 2.1.4 Mutations Affecting Large Regions of DNA Sequences; 2.2 Nucleotide Substitutions 2.2.1 Basic Characteristics of Nucleotide Substitutions2.2.2 Nucleotide Substitutions in Protein Coding Regions; 2.2.3 Methylation Creates "Fifth" Nucleotide; 2.3 Insertion and Deletion; 2.3.1 Basic Characteristics of Insertions and Deletions; 2.3.2 Insertions and Deletions of Unique Sequences; 2.3.3 Insertions and Deletions of Repeat Sequences; 2.4 Recombination and Gene Conversion; 2.4.1 Nature of Gene Conversion; 2.4.2 Gene Conversion on Duplog Pairs; 2.5 Gene Duplication; 2.5.1 Classification of Duplication Events; 2.5.2 Drift Duplication; 2.5.3 Genome Duplication 2.6 Estimation of Mutation Rates2.6.1 Direct and Indirect Method; 2.6.2 Direct Method; 2.6.3 Indirect Methods; 2.6.4 Mutation Rates of Bacteria, Organella, and Viruses; 2.7 Mutation Affecting Phenotypes; 2.7.1 What Is Phenotype?; 2.7.2 Mutations in Protein Coding Region; 2.7.3 Mutations in Noncoding Region; References; Additional Citations Not Ordered According to Text Locations; 3: Phylogeny; 3.1 DNA Replications Generate Phylogenies; 3.2 Genealogy of Individuals; 3.2.1 Genealogy of Haploid Individuals; 3.2.2 Genealogy of Diploid Individuals 3.2.3 Paternal or Maternal Genealogy of Diploid Individuals3.3 Gene Genealogy; 3.3.1 When a Gene Tree Is Identical to a Genome Tree; 3.3.2 Gene Phylogenies in Diploids; 3.3.3 Three Layers of Gene Phylogenies; 3.3.4 Orthology and Paralogy; 3.3.5 Gene Conversions May Twist the Gene Tree; 3.3.6 Horizontal Gene Transfer and Xenology; 3.4 Species Phylogeny; 3.4.1 Two Layers of Species Trees; 3.4.2 Gene Tree as the Approximation of Species Tree; 3.4.3 Gene Tree May Be Different from Species Tree; 3.5 Basic Concepts of Trees and Networks; 3.5.1 Mathematical Definition
Series Title: Computational Biology Ser., 17.

Abstract:

This book describes core processes of replication, mutation, neutral evolution and natural selection, genome evolution in prokaryotes, eukaryotes, vertebrates and humans, genome sequencing amd more,  Read more...

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