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The kidney : from normal development to congenital diseases

Author: Peter D Vize; Adrian S Woolf; Johnathan B L Bard
Publisher: Amsterdam ; Boston : Academic Press, ©2003.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Kidney.
Amsterdam ; Boston : Academic Press, ©2003
(DLC) 2002107395
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Peter D Vize; Adrian S Woolf; Johnathan B L Bard
ISBN: 9780127224411 0127224416 9780080521541 0080521541
OCLC Number: 648244617
Description: 1 online resource (xiii, 519 pages) : illustrations (chiefly color)
Contents: Foreword --
SECTION 1: EMBRYONIC KIDNEYS AND MODELS --
1. Introduction: the embryonic kidneys and other nephrogenic models --
2. Development of the Malpighian tubules in Drosophila melanogaster --
3. Induction, development and physiology of the pronephric tubules --
4. Formation of the nephric duct --
5. The pronephric glomus and vasculature --
6. Development of the mesonephric kidney --
7. 3-Dimensional anatomy of mammalian mesonephroi --
8. The Molecular control of pronephros development- an Overview --
9. Embryological, genetic and molecular tools for investigating embryonic kidney development --
SECTION 2: THE ADULT KIDNEYS --
10. Introduction --
11. Anatomy and Histology of the Human Urinary System --
12. Development of the Ureteric Bud --
13. The Fates of the Metanephric Mesenchyme --
14. The Formation and Development of Nephrons --
15. Establishment of polarity in epithelial cells of the developing nephron --
16. Development of the Glomerular Capillary and its Basement Membrane --
17. The development of kidney blood vessels --
18. The Development of function in the metanephric kidney --
19. Experimental methods for studying urogenital development --
20. Overview: The Molecular Basis of Kidney Development --
SECTION 3: CONGENITAL DISEASE --
21. Maldevelopment of the Human Kidney and Lower Urinary Tract: an Overview --
22. Wilms' Tumor and related disorders --
23. Pax-2 and Renal-Coloboma Syndrome --
24. Polycystic Kidney Disease, von Hippel Lindau and Tuberous sclerosis --
26. Renal Cell Carcinoma: The Human Disease --
27. The Tubule --
28. Diseases of the Glomerular Filtration Barrier: Alport Syndrome and Congenital Nephrosis (NPHS1) --
29. Congenital Kidney Diseases: Prospects for New Therapies.
Responsibility: edited by Peter D. Vize, Adrian S. Woolf, Jonathan B.L. Bard.
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Abstract:

Organogenesis of the kidney has been intensely studied. Advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began  Read more...

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"well organized and well written...an outstanding reference for clinical pediatric nephrologists and urologists."- Sandeep Soman, TRENDS IN ENDOCRINOLOGY AND METABOLISM (August 2004)"...an excellent Read more...

 
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