Management of Chronic Gastrointestinal Ischemia (Book, 2012) [WorldCat.org]
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Management of Chronic Gastrointestinal Ischemia

Author: Aria Sana
Publisher: Erasmus University Rotterdam 2012-09-26
Edition/Format: Book Book : English
Summary:
textabstractGastrointestinal ischemia results from a mismatch of blood supply to the main gastrointestinalarteries and the oxygen demand to maintain adequate metabolism. Three aorticbranches supply blood to the gastrointestinal tract: the celiac artery, the superior mesentericartery, and the inferior mesenteric artery. One of the main causes of chronic gastrointestinalischemia (CGI) is stenotic or occlusive disease  Read more...
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Details

Document Type: Book
All Authors / Contributors: Aria Sana
ISBN: 978-94-6169-294-8
Language Note: English
Unique Identifier: 6892889985
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Abstract:

textabstractGastrointestinal ischemia results from a mismatch of blood supply to the main gastrointestinalarteries and the oxygen demand to maintain adequate metabolism. Three aorticbranches supply blood to the gastrointestinal tract: the celiac artery, the superior mesentericartery, and the inferior mesenteric artery. One of the main causes of chronic gastrointestinalischemia (CGI) is stenotic or occlusive disease of the supplying gastrointestinal arteries. Fora long time it was thought that only occlusive disease of two or more gastrointestinal arteriescould lead to CGI. The introduction of functional testing has played a pivotal role in thediagnosis of CGI. Functional testing has shown that CGI is more common than previouslythought because it can also be caused by single vessel disease. Further studies showed thata majority of patients with single vessel disease had sustained response after adequate treatment.Moreover, functional testing seems to be pivotal to select patients who will benefitfrom treatment, whether the cause is single- or multi-vessel disease.In this thesis we aimed to study different aspects of diagnosis and treatment of CGI. Westudied the predictive value of functional testing in diagnosis of CGI, and determined thediagnostic accuracy of a new minimally invasive technique to detect ischemia in order tooptimize the diagnosis of CGI. Furthermore, we assessed the risk factors for atheroscleroticdisease of the abdominal arteries, being one of the main causes of CGI. We also evaluatedthe clinical success of revascularization in single vessel disease and response to vasodilationtherapy in patients with non-occlusive CGI.

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