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Melatonin: from molecules to therapy

Author: Daniel P Cardinali; S R Pandi-Perumal
Publisher: New York, NY : Nova Biomedical Books, ©2007.
Edition/Format:  Print book : EnglishView all editions and formats
Summary:

Melatonin is a neurohormone produced in the brain by the pineal gland, from the amino acid tryptophan. Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Daniel P Cardinali; S R Pandi-Perumal
ISBN: 1600211216 9781600211218
OCLC Number: 255379909
Description: XVI, 906 Seiten : Illustrationen, Diagramme
Contents: Preface; Chromatographic Analyses of Biogenic Melatonin and Its Related Indoleamines; 5-Methoxylated Kynuramines: Biologically Active Melatonin Metabolites and Sources of New Products; Advances on the Development of Subtype Selective Melatonin Ligands; The interaction between melatonin and calmodulin: a NMR and molecular dynamics study; The low affinity binding of melatonin to calmodulin: use of computational methods to explain its physiological relevance; Neural regulation of melatonin synthesis; Regulation of melatonin Synthesis: Animal versus Human Studies; Toward a chronome (time structure) of melatonin; Chronobiological aspects of melatonin activity; The molecular basis to the circadian effects of melatonin; Melatonin effects on uterine physiology; Melatonin and Human Reproduction: Why the effect is so elusive?; Melatonin: Immunomodulatory Signal; Photoperiodic vs. non-photoperiodic animals circadian and seasonal changes in immunity; Melatonin: an endogenous antiestrogen with oncostatic properties; Melatonin and Cancer: Basic Research; Melatonin in retinal pathophysiology; The physiology, pharmacology, and anatomical distribution of melatonin receptors in visual system nuclei in the vertebrate CNS; Antioxidant capacity of the neurohormone melatonin; Protective role of melatonin against mitochondrial damage in inflammation; Protective effects of melatonin against hyperhomocysteinemia; Photo- and radiation induced reactions of melatonin by laser photolysis and pulse radioloysis; Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain; Melatonin Receptors in Neuroendocrine Development; The effects of exogenous melatonin on the morphology of thyrocytes in pinealectomised and irradiated rats; The control of Melatonin release from mammalian and avian pineal glands; Effects of chronic melatonin administration on various physiological parameters from old wistar rats; Pineal region tumours; Melatonin and Cancer: therapeutic perspectives; Therapeutic perspectives of gastrointestinal melatonin; Endogenous Versus Exogenous Effects of Melatonin; ; Melatonin Circadian Rhythms in Women with Depression: Relationship to the Reproductive Cycle; Melatonin therapy of circadian rhythm sleep disorders in neurodevelopmentally disordered children: a neurological viewpoint; Treatment by melatonin of a genetic disorder: Smith-Magenis syndrome; Melatonin and sleep in shift-workers; Role of Melatonin in the regulation of human circadian rhythms and sleep; Ramelteon, a selective MT1/MT2 receptor agonist, provides a novel treatment for insomnia; Melatonin, Dopamine and Circadian Rhythm in the Restless Legs Syndrome; Sleep and Circadian Neuroendocrine Dysregulation in Seasonal Affective Disorder; Involvement of free radicals and reactive oxygen species in physiological and pathological processes in the thyroid gland; a potential role of melatonin; Role of melatonin in Headache disorders; Ambient illumination and melatonin in the natural setting; Melatonin: effects on smooth muscle and clinical utility; Melatonin and woman; Effects of Melatonin on Cardiovascular System; Melatonin and cerebrovascular disease; Melatonin in Focal Cerebral Ischaemia: Evidence for efficacy and priorities for future research; Understanding the role of melatonin in epilepsy: from bench to bedside; Role of Melatonin on Alzheimers disease; Longitudinal measurements of melatonin secretion in the elderly: Implications for Alzheimers Disease; Interactions of Melatonin With Environmental Factors.
Responsibility: S.R. Pandi-Perumal ; Daniel P. Cardinali, eds.
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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/149139025#Topic\/pineal_gland_secretion<\/a>> # Pineal Gland; secretion<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:hasPart<\/a> <http:\/\/id.loc.gov\/authorities\/subjects\/sh85102232<\/a>> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Pineal Gland; secretion<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Pineal gland--Secretion<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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<http:\/\/id.worldcat.org\/fast\/810647<\/a>> # Antioxidants--Therapeutic use<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Antioxidants--Therapeutic use<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.worldcat.org\/fast\/967993<\/a>> # Immunological adjuvants--Therapeutic use<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Immunological adjuvants--Therapeutic use<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/viaf.org\/viaf\/4192173<\/a>> # Daniel P. Cardinali<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Cardinali<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Daniel P.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Daniel P. Cardinali<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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Content-negotiable representations<\/p>\n