skip to content
Metallo-drugs : development and action of anticancer agents Preview this item
ClosePreview this item
Checking...

Metallo-drugs : development and action of anticancer agents

Author: Enzo AlessioWee Han AngMaria V BabakSusan Berners-PriceVictor BrabecAll authors
Publisher: Berlin ; Boston : Walter de Gruyter GmbH, [2018] ©2018
Series: Metal ions in life sciences, v. 18.
Edition/Format:   eBook : Document : Government publication : EnglishView all editions and formats
Summary:
Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity,  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
(DLC) 2018001061
(OCoLC)1019838900
Material Type: Document, Government publication, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Enzo Alessio; Wee Han Ang; Maria V Babak; Susan Berners-Price; Victor Brabec; A Casini; Nicholas P Farrell; Eva Freisinger; Anil K Gorle; Jana Kasparkova; Stephen J Lippard; Vijay Menon; Luigi Messori; Erica J Peterson; Imogen Riddell; Peter J Sadler; Astrid Sigel; Helmut Sigel; Roland K O Sigel; V Venkatesh
ISBN: 9783110470734 311047073X 9783110470741 3110470748 3110469901 9783110469905
OCLC Number: 1024024707
Language Note: In English.
Description: 1 online resource (588 pages)
Contents: About the editors --
Historical development and perspectives of the series / Astrid Sigel, Helmut Sigel, Roland K.O. Sigel --
Preface to volume 18 / Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel --
Contributors to volume 18. --
1. Cisplatin and oxaliplatin : our current understanding of their actions / Imogen A. Riddell, Stephen J. Lippard --
2. Polynuclear platinum complexes : structural diversity and DNA binding / Viktor Brabec, Jana Kasparkova, Vijay Menon, Nicholas P. Farrell --
3. Platinum(IV) prodrugs / V. Venkatesh, Peter J. Sadler --
4. Metalloglycomics / Nicholas P. Farrell, Anil K. Gorle, Erica J. Peterson, Susan J. Berners-Price --
5. The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Enzo Alessio, Luigi Messori --
6. Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Maria V. Babak, Wee Han Ang --
7. Medicinal chemistry of gold anticancer metallodrugs / Angela Casini, Raymond Wai-Yin Sun, Ingo Ott --
8. Coordination complexes of titanium(IV) for anticancer therapy / Edit Y. Tshuva, Maya Miller --
9. Health benefits of vanadium and its potential as an anticancer agent / Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang --
10. Gallium complexes as anticancer drugs / Christopher R. Chitambar --
11. Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Lucia Cardo, Michael J. Lucia --
12. Nucleic acid quadruplexes and metallo-drugs / Ramon Vilar --
13. Antitumor metallodrugs that target proteins / Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger --
14. Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Ulrich Schatzschneider --
15. Iron and its role in cancer defense : a double-edged sword / Frank Thévenod --
16. Copper complexes in cancer therapy / Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater --
17. Targeting zinc(II) signalling to prevent cancer / Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor --
Subject index.
Series Title: Metal ions in life sciences, v. 18.
Responsibility: edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel.
More information:

Abstract:

Cisplatin has been saving lives for over 40 years, yet our understanding of its molecular-level action in cells and the biochemical consequences continues to deepen. Modern biological research  Read more...

Reviews

Editorial reviews

Publisher Synopsis

"The editors are to be congratulated for not only keeping the scientific community abreast of latest developments in this vibrant field of research but for providing an invaluable resource which will Read more...

 
User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/1024024707> # Metallo-drugs : development and action of anticancer agents
    a schema:MediaObject, schema:CreativeWork, schema:Book ;
    library:oclcnum "1024024707" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/gw> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/4724776313#Topic/pharmaceutical_chemistry> ; # Pharmaceutical chemistry
    schema:about <http://dewey.info/class/615.798/e23/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/4724776313#Topic/antineoplastic_agents> ; # Antineoplastic agents
    schema:about <http://experiment.worldcat.org/entity/work/data/4724776313#Topic/medical_pharmacology> ; # MEDICAL--Pharmacology
    schema:about <http://experiment.worldcat.org/entity/work/data/4724776313#Topic/cisplatin> ; # Cisplatin
    schema:about <http://experiment.worldcat.org/entity/work/data/4724776313#Topic/organoplatinum_compounds_therapeutic_use> ; # Organoplatinum Compounds--therapeutic use
    schema:bookFormat schema:EBook ;
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/farrell_nicholas_p> ; # Nicholas P. Farrell
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/babak_maria_v> ; # Maria V. Babak
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/lippard_stephen_j> ; # Stephen J. Lippard
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/venkatesh_v> ; # V. Venkatesh
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/alessio_enzo> ; # Enzo Alessio
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/berners_price_susan> ; # Susan Berners-Price
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/menon_vijay> ; # Vijay Menon
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/peterson_erica_j> ; # Erica J. Peterson
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/brabec_victor> ; # Victor Brabec
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/kasparkova_jana> ; # Jana Kasparkova
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/ang_wee_han> ; # Wee Han Ang
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/casini_a> ; # A. Casini
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/sadler_peter_j> ; # Peter J. Sadler
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/gorle_anil_k> ; # Anil K. Gorle
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/riddell_imogen> ; # Imogen Riddell
    schema:contributor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/messori_luigi> ; # Luigi Messori
    schema:datePublished "2018" ;
    schema:description "Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching."@en ;
    schema:editor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_astrid> ; # Astrid Sigel
    schema:editor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_roland_k_o> ; # Roland K. O. Sigel
    schema:editor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/freisinger_eva> ; # Eva Freisinger
    schema:editor <http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_helmut> ; # Helmut Sigel
    schema:exampleOfWork <http://worldcat.org/entity/work/id/4724776313> ;
    schema:genre "Government publication"@en ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://worldcat.org/issn/1559-0836> ; # Metal ions in life sciences ;
    schema:isSimilarTo <http://worldcat.org/entity/work/data/4724776313#CreativeWork/> ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/1019838900> ;
    schema:name "Metallo-drugs : development and action of anticancer agents"@en ;
    schema:productID "1024024707" ;
    schema:url <https://public.ebookcentral.proquest.com/choice/publicfullrecord.aspx?p=5157376> ;
    schema:url <https://doi.org/10.1515/9783110470734> ;
    schema:url <http://www.vlebooks.com/vleweb/product/openreader?id=none&isbn=9783110470734> ;
    schema:url <https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1710663> ;
    schema:url <http://www.vlebooks.com/vleweb/product/openreader?id=none&isbn=9783110469905> ;
    schema:workExample <http://worldcat.org/isbn/9783110470734> ;
    schema:workExample <http://worldcat.org/isbn/9783110470741> ;
    schema:workExample <http://dx.doi.org/10.1515/9783110470734> ;
    schema:workExample <http://worldcat.org/isbn/9783110469905> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/1024024707> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/alessio_enzo> # Enzo Alessio
    a schema:Person ;
    schema:familyName "Alessio" ;
    schema:givenName "Enzo" ;
    schema:name "Enzo Alessio" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/ang_wee_han> # Wee Han Ang
    a schema:Person ;
    schema:familyName "Ang" ;
    schema:givenName "Wee Han" ;
    schema:name "Wee Han Ang" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/babak_maria_v> # Maria V. Babak
    a schema:Person ;
    schema:familyName "Babak" ;
    schema:givenName "Maria V." ;
    schema:name "Maria V. Babak" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/berners_price_susan> # Susan Berners-Price
    a schema:Person ;
    schema:familyName "Berners-Price" ;
    schema:givenName "Susan" ;
    schema:name "Susan Berners-Price" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/brabec_victor> # Victor Brabec
    a schema:Person ;
    schema:familyName "Brabec" ;
    schema:givenName "Victor" ;
    schema:name "Victor Brabec" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/casini_a> # A. Casini
    a schema:Person ;
    schema:familyName "Casini" ;
    schema:givenName "A." ;
    schema:name "A. Casini" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/farrell_nicholas_p> # Nicholas P. Farrell
    a schema:Person ;
    schema:familyName "Farrell" ;
    schema:givenName "Nicholas P." ;
    schema:name "Nicholas P. Farrell" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/freisinger_eva> # Eva Freisinger
    a schema:Person ;
    schema:familyName "Freisinger" ;
    schema:givenName "Eva" ;
    schema:name "Eva Freisinger" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/gorle_anil_k> # Anil K. Gorle
    a schema:Person ;
    schema:familyName "Gorle" ;
    schema:givenName "Anil K." ;
    schema:name "Anil K. Gorle" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/kasparkova_jana> # Jana Kasparkova
    a schema:Person ;
    schema:familyName "Kasparkova" ;
    schema:givenName "Jana" ;
    schema:name "Jana Kasparkova" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/lippard_stephen_j> # Stephen J. Lippard
    a schema:Person ;
    schema:familyName "Lippard" ;
    schema:givenName "Stephen J." ;
    schema:name "Stephen J. Lippard" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/menon_vijay> # Vijay Menon
    a schema:Person ;
    schema:familyName "Menon" ;
    schema:givenName "Vijay" ;
    schema:name "Vijay Menon" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/messori_luigi> # Luigi Messori
    a schema:Person ;
    schema:familyName "Messori" ;
    schema:givenName "Luigi" ;
    schema:name "Luigi Messori" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/peterson_erica_j> # Erica J. Peterson
    a schema:Person ;
    schema:familyName "Peterson" ;
    schema:givenName "Erica J." ;
    schema:name "Erica J. Peterson" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/riddell_imogen> # Imogen Riddell
    a schema:Person ;
    schema:familyName "Riddell" ;
    schema:givenName "Imogen" ;
    schema:name "Imogen Riddell" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/sadler_peter_j> # Peter J. Sadler
    a schema:Person ;
    schema:familyName "Sadler" ;
    schema:givenName "Peter J." ;
    schema:name "Peter J. Sadler" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_astrid> # Astrid Sigel
    a schema:Person ;
    schema:familyName "Sigel" ;
    schema:givenName "Astrid" ;
    schema:name "Astrid Sigel" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_helmut> # Helmut Sigel
    a schema:Person ;
    schema:familyName "Sigel" ;
    schema:givenName "Helmut" ;
    schema:name "Helmut Sigel" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/sigel_roland_k_o> # Roland K. O. Sigel
    a schema:Person ;
    schema:familyName "Sigel" ;
    schema:givenName "Roland K. O." ;
    schema:name "Roland K. O. Sigel" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Person/venkatesh_v> # V. Venkatesh
    a schema:Person ;
    schema:familyName "Venkatesh" ;
    schema:givenName "V." ;
    schema:name "V. Venkatesh" ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Topic/antineoplastic_agents> # Antineoplastic agents
    a schema:Intangible ;
    schema:name "Antineoplastic agents"@en ;
    schema:name "Antineoplastic Agents"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Topic/medical_pharmacology> # MEDICAL--Pharmacology
    a schema:Intangible ;
    schema:name "MEDICAL--Pharmacology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Topic/organoplatinum_compounds_therapeutic_use> # Organoplatinum Compounds--therapeutic use
    a schema:Intangible ;
    schema:name "Organoplatinum Compounds--therapeutic use"@en ;
    schema:name "Organoplatinum compounds--Therapeutic use"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/4724776313#Topic/pharmaceutical_chemistry> # Pharmaceutical chemistry
    a schema:Intangible ;
    schema:name "Pharmaceutical chemistry"@en ;
    .

<http://worldcat.org/entity/work/data/4724776313#CreativeWork/>
    a schema:CreativeWork ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/1024024707> ; # Metallo-drugs : development and action of anticancer agents
    .

<http://worldcat.org/isbn/9783110469905>
    a schema:ProductModel ;
    schema:isbn "3110469901" ;
    schema:isbn "9783110469905" ;
    .

<http://worldcat.org/isbn/9783110470734>
    a schema:ProductModel ;
    schema:isbn "311047073X" ;
    schema:isbn "9783110470734" ;
    .

<http://worldcat.org/isbn/9783110470741>
    a schema:ProductModel ;
    schema:isbn "3110470748" ;
    schema:isbn "9783110470741" ;
    .

<http://worldcat.org/issn/1559-0836> # Metal ions in life sciences ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/1024024707> ; # Metallo-drugs : development and action of anticancer agents
    schema:issn "1559-0836" ;
    schema:name "Metal ions in life sciences ;" ;
    schema:name "Metal ions in life sciences," ;
    .

<http://www.worldcat.org/oclc/1019838900>
    a schema:CreativeWork ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/1024024707> ; # Metallo-drugs : development and action of anticancer agents
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.