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Microbiome and cancer

Author: Erle S Robertson
Publisher: Cham, Switzerland : Humana Press, 2019.
Series: Current cancer research
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Microbiome and cancer.
Cham, Switzerland : Humana Press, 2019
(OCoLC)1056741307
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Erle S Robertson
ISBN: 9783030041557 3030041557
OCLC Number: 1088555134
Notes: Includes index.
Description: 1 online resource (xiv, 401 pages) : illustrations (some color)
Contents: Intro; Preface; Contents; Contributors; Chapter 1: Microbiome and Human Malignancies; 1.1 Introduction; 1.2 Technological Advancement In Lieu of Microbes Associated Cancers; 1.3 Cancer Associated Microorganisms; 1.4 Immune Influence by Microbiota in Promoting Cancer; 1.5 Microbes in Cancer Therapy; 1.6 Conclusion and Future Perspectives; References; Chapter 2: Infection Based Gastric Cancer; 2.1 Infection-Associated Cancers; 2.2 Gastric Cancer; 2.3 Factors That Influence Gastric Carcinogenesis; 2.3.1 Host Genetics; 2.3.2 The Environment; 2.3.3 Infectious Agents; 2.3.3.1 H. pylori 2.3.3.2 H. pylori Virulence Factors2.3.4 Epstein-Barr Virus (EBV); 2.3.5 The Human Gastric Microbiome; 2.3.6 The Rodent Gastric Microbiome; 2.4 Conclusions; References; Chapter 3: Role of Infectious Agents on Development of Esophageal Carcinomas; 3.1 Introduction; 3.2 Bacteria and Esophageal Carcinoma; 3.2.1 Esophageal Microbiome; 3.2.2 Oral Microbiome; 3.2.3 Gastric Microbiome; 3.2.4 Helicobacter pylori; 3.2.5 Targeting the Microbiome to Improve Esophageal Cancer Outcomes; 3.3 Viruses and Esophageal Carcinoma; 3.3.1 Human Papilloma Viruses; 3.3.2 Herpesviridae; 3.3.2.1 Epstein-Barr Virus 3.3.2.2 Herpes Simplex Virus3.3.2.3 Cytomegalovirus; 3.3.2.4 Varicella-Zoster Virus; 3.3.3 Human Immunodeficiency Virus; 3.4 Fungi and Esophageal Carcinoma; 3.5 Parasites and Esophageal Carcinoma; References; Chapter 4: Viruses and Glioblastoma: Affliction or Opportunity?; 4.1 Introduction to Glioblastoma; 4.2 Detection of Viral Particles in Glioblastoma Cells; 4.2.1 Herpesviruses; 4.2.1.1 Epstein-Barr Virus; 4.2.1.2 Cytomegalovirus; 4.2.1.3 Human Herpesvirus 6; 4.2.2 Polyomaviruses; 4.2.2.1 Simian Virus 40; 4.2.2.2 John Cunningham Virus; 4.2.2.3 B.K. Virus; 4.2.3 Human Papillomavirus 4.3 Effects of Viral Infection on Glioblastoma Progression4.3.1 Oncomodulatory Proteins and Polynucleotides; 4.3.1.1 Polyomavirus Large Tumor Antigen; 4.3.1.2 HHV-6 ORF-1; 4.3.1.3 Cytomegalovirus Antigens and MicroRNA; 4.3.2 Viral Cofactors; 4.3.3 Viral-Mediated Immunomodulation; 4.3.3.1 Inflammation; 4.3.3.2 Immunosuppression and Immune Evasion; 4.4 Antivirals: A Suitable Therapy for GBM?; 4.4.1 Antiviral Agents; 4.4.2 Virus-Targeted Immunotherapy; 4.5 Conclusion; References; Chapter 5: The Microbiome and Its Contribution to Skin Cancer; 5.1 Introduction 5.2 Kaposi Sarcoma and Kaposi Sarcoma Herpesvirus5.2.1 Discovery; 5.2.2 Epidemiology; 5.2.3 Mechanisms of Carcinogenesis; 5.2.4 Controversies and Open Questions in the Field; 5.3 Merkel Cell Carcinoma and Merkel Cell Polyomavirus; 5.3.1 Discovery; 5.3.2 Epidemiology; 5.3.3 Mechanisms of Carcinogenesis; 5.3.4 Controversies and Open Questions in the Field; 5.4 Cutaneous Squamous Cell Carcinoma and Human Papillomavirus; 5.4.1 Discovery; 5.4.2 Epidemiology; 5.4.3 Mechanisms of Carcinogenesis; 5.4.4 Controversies and Open Questions in the Field; 5.5 Bacterial Skin Commensals and Skin Cancers
Series Title: Current cancer research
Responsibility: Erle S. Robertson, editor.

Abstract:

Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin's and non-Hodgkin's lymphomas, glioblastoma  Read more...

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