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Mitochondrial DNA and diseases

Author: Hongzhi Sun; Xiangdong Wang, (Professor of clinical bioinformatics)
Publisher: Singapore : Springer, 2017.
Series: Advances in experimental medicine and biology, v. 1038.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of  Read more...
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Genre/Form: Electronic book
Electronic books
Additional Physical Format: Print version:
Sun, Hongzhi.
Mitochondrial DNA and Diseases.
Singapore : Springer Singapore Pte. Limited, ©2017
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Hongzhi Sun; Xiangdong Wang, (Professor of clinical bioinformatics)
ISBN: 9789811066740 9811066744
OCLC Number: 1013828874
Description: 1 online resource (233 pages)
Contents: How far can mitochondrial DNA drive the disease? --
Mitochondrial DNA in lung cancer --
Approach, application and bioethics of mtDNA sequencing in cancer --
Roles of mitochondrial DNA signaling in immune responses --
Mitochondrial DNA in Telocytes --
Roles of mitochondrial DNA in energy metabolism --
The role of base excision repair in maintaining mitochondrial DNA stability.- Is mitochondrial cell fragility a cell weakness? --
Mitochondrial DNA methylation and related disease --
Beyond deubiquitylation: USP30-mediated regulation of mitochondrial homeostasis --
Metabolic regulation in mitochondria and drug resistance.- Mitochondrial Lon Protease and Cancer --
Regulatory roles of mitochondrial ribosome in lung diseases and single cell biology.-Epithelial mitochondrial dysfunction in lung disease.
Series Title: Advances in experimental medicine and biology, v. 1038.
Responsibility: Hongzhi Sun, Xiangdong Wang, editors.

Abstract:

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. This book covers not only  Read more...

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