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Modelling optimization and control of biomedical systems

Author: Efstratios N Pistikopoulos; Ioana Naşcu; Eirini G Velliou
Publisher: Hoboken, NJ : John Wiley & Sons, 2018. ©2018
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Shows the newest developments in the field of multi-parametric model predictive control and optimization and their application for drug delivery systems This book is based on the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project, which was created to derive intelligent computer model-based systems for optimization of biomedical drug delivery systems in the cases of diabetes, anaesthesia, and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Modelling optimization and control of biomedical systems.
Hoboken, NJ : John Wiley & Sons, 2018
(DLC) 2017024242
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Efstratios N Pistikopoulos; Ioana Naşcu; Eirini G Velliou
ISBN: 9781118965566 1118965566 9781118965580 1118965582 1118965590 9781118965597 9781523118397 1523118393
OCLC Number: 1002302716
Notes: Includes index.
Description: 1 online resource
Contents: Framework and Tools / Eirini G Velliou, Ioana Naşcu, Stamatina Zavitsanou, Eleni Pefani, Alexandra Krieger, Michael C Georgiadis, Efstratios N Pistikopoulos --
Draft Computational Tools and Methods / Ioana Naşcu, Richard Oberdieck, Romain Lambert, Pedro Rivotti, Efstratios N Pistikopoulos --
Volatile Anaesthesia / Alexandra Krieger, Ioana Naşcu, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C Georgiadis, Efstratios N Pistikopoulos --
Intravenous Anaesthesia / Ioana Naşcu, Alexandra Krieger, Romain Lambert, Efstratios N Pistikopoulos --
Part A: Type 1 Diabetes Mellitus / Stamatina Zavitsanou, Athanasios Mantalaris, Michael C Georgiadis, Efstratios N Pistikopoulos --
An Integrated Platform for the Study of Leukaemia / Eirini G Velliou, Maria Fuentes-Gari, Ruth Misener, Eleni Pefani, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C Georgiadis, Efstratios N Pistikopoulos --
In vitro Studies / Eirini G Velliou, Eleni Pefani, Susana Brito dos Santos, Maria Fuentes-Gari, Ruth Misener, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C Georgiadis, Efstratios N Pistikopoulos --
In silico Acute Myeloid Leukaemia / Eleni Pefani, Eirini G Velliou, Nicki Panoskaltsis, Athanasios Mantalaris, Michael C Georgiadis, Efstratios N Pistikopoulos.
Responsibility: edited by Efstratios N. Pistikopoulos, Ioana Naşcu, Eirini G. Velliou.

Abstract:

Shows the newest developments in the field of multi-parametric model predictive control and optimization and their application for drug delivery systems This book is based on the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project, which was created to derive intelligent computer model-based systems for optimization of biomedical drug delivery systems in the cases of diabetes, anaesthesia, and blood cancer. These systems can ensure reliable and fast calculation of the optimal drug dosage without the need for an online computer—while taking into account the specifics and constraints of the patient model, flexibility to adapt to changing patient characteristics and incorporation of the physician's performance criteria, and maintaining the safety of the patients. Modelling Optimization and Control of Biomedical Systems covers: mathematical modelling of drug delivery systems; model analysis, parameter estimation, and approximation; optimization and control; sensitivity analysis & model reduction; multi-parametric programming and model predictive control; estimation techniques; physiologically-based patient model; control design for volatile anaesthesia; multiparametric model based approach to intravenous anaesthesia; hybrid model predictive control strategies; Type I Diabetes Mellitus; in vitro and in silico block of the integrated platform for the study of leukaemia; chemotherapy treatment as a process systems application; and more. Introduces readers to the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project Presents in detail the theoretical background, computational tools, and methods that are used in all the different biomedical systems Teaches the theory for multi-parametric mixed-integer programming and explicit optimal control of volatile anaesthesia Provides an overview of the framework for modelling, optimization, and control of biomedical systems This book will appeal to students, researchers, and scientists working on the modelling, control, and optimization of biomedical systems and to those involved in cancer treatment, anaesthsia, and drug delivery systems.

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These systems can ensure reliable and fast calculation of the optimal drug dosage without the need for an online computer\u2014while taking into account the specifics and constraints of the patient model, flexibility to adapt to changing patient characteristics and incorporation of the physician\'s performance criteria, and maintaining the safety of the patients. 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