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The molecular and cellular biology of fertilization

Author: Jerry L Hedrick; University of California, Davis. Division of Biological Sciences.
Publisher: New York : Plenum Press, ©1986.
Series: Advances in experimental medicine and biology, v. 207.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:
This book is derived from presentations made at the Symposium held at the University of California, Davis, on June 20-22, 1984, This 75th Anniversary Symposium was sponsored by the Division of Biological Sciences, Donald L. McLean, Dean, and was organized in celebration of the founding of the Davis campus of the University of California. I am indebted to the members of the Organizing Committee, W.H. Clark, R.D.  Read more...
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Genre/Form: Congresses
Conference papers and proceedings
Congress
Congrès
Additional Physical Format: Online version:
Symposium on the Molecular and Cellular Biology of Fertilization (1984 : University of California, Davis).
Molecular and cellular biology of fertilization.
New York : Plenum Press, ©1986
(OCoLC)761091747
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Jerry L Hedrick; University of California, Davis. Division of Biological Sciences.
ISBN: 0306424789 9780306424786
OCLC Number: 14413150
Notes: "Proceedings of the Seventy-Fifth Annual Symposium on the Molecular and Cellular Biology of Fertilization, held June 20-22, 1984, at the University of California, Davis, in Davis, California"--Title page verso.
This 75th anniversary symposium was organized in celebration of the founding of the Davis campus of the University of California and sponsored by its Division of Biological Sciences.
Description: xviii, 452 pages : illustrations ; 26 cm.
Contents: Prologue.- 1 Fertilization and Immunity-Revisited.- Summary.- Univalent Antibodies.- Paramecium: A Model System.- References.- 2 Sperm-Egg Interactions Preparatory to Fertilization.- Summary.- The Activation of the Spermatozoon.- The Activation of the Egg.- Concluding Remarks.- References.- 3 Effects of Anti-Zona Pellucida Monoclonal Antibodies on Fertilization and Early Development.- Summary.- Monoclonal Antibodies.- Passive Immunization of Mice.- In Vitro Fertilization and Development.- Production of Monoclonal Antibodies.- Distribution of Zona Proteins.- Passive Immunization of Mice.- In Vitro Fertilization.- Reversibility of Contraception.- Effect on Development.- Discussion.- References.- 4 Nature of the Mouse Egg's Receptor for Sperm.- Summary.- Composition of the Mouse Zona Pellucida.- Identification of the Mouse Egg's Sperm Receptor: Experimental Approach.- Identification of the Mouse Egg's Sperm Receptor: Observations.- Identification of the Mouse Egg's Inducer of the Acrosome Reaction: Experimental Approach.- Identification of the Mouse Egg's Inducer of the Acrosome Reaction: Observations.- Structure of ZP3: The Mouse Egg's Receptor for Sperm.- Identification of the Molecular Nature of the Sperm Receptor Activity of ZP3.- Identification of the Molecular Nature of the Acrosome Reaction-Inducing Activity of ZP3.- Discussion.- References.- 5 The Receptor Function of Galactosyltransferase During Mammalian Fertilization.- Summary.- Cell Surface GalTase.- The T/t-Complex of the Mouse.- Surface GalTase on Mutant t-Sperm.- The Effects of In Vitro Capacitation on Surface GalTase Activity.- Perturbing Sperm GalTase Inhibits Sperm/Egg Binding.- Inhibition of Sperm/Zona Binding by Purified GalTase.- Inhibition of Sperm/Zona Binding by Monospecific Anti-GalTAse IgG.- Sperm GalTase Substrates in the Zona Pellucida.- Conclusions.- References.- 6 Immunological Identification of Sperm Antigens that Participate in Fertilization.- Summary.- Acrosomal Crescent Localization: M42 and M41.- Equatorial Segment Localization: M2 and M29.- References.- 7 The Action Of Acrosin on the Zona Pellucida.- Summary.- Materials and Methods.- Results and Discussion.- Conclusions.- References.- 8 Biochemical Studies of the Envelope Transformations in XenopusLaevis Eggs.- Summary.- Biological Features.- Morphological Approach.- Molecular Approach.- CE to VE Conversion.- VE to FE Conversion.- Concluding Comments.- References.- 9 The Role of Oviducal Secretions in Mediating Gamete Fusion in the Toad, BufoBufoJaponicus.- Summary.- Materials and Methods.- Results and Discussion.- Concluding Remarks.- References.- 10 Oviducal Pars Recta as Factor in Fertilization Properties and Hormonal Regulation in the Toad BufoArenarum.- Summary.- Involvement of Pars Recta in Fertilization.- Structural Change of the Coelomic Oocytes Vitelline Envelope by Oviducal Secretion.- Ultrastructural Study.- Participation of Pars Recta in Inducing Acrosome Reaction.- Metabolic Switch in Coelomic Oocytes of PR Effect.- Comparative Biological and Biochemical Properties of Pars Recta Secretion Fluid and Protein(s) Purified from Pars Recta Extract.- Hormonal Regulation of Biological Activity.- Conclusions.- References.- 11 The Cortical Endoplasmic Reticulum and its Possible Role in Activation of DiscoglossusPictis (Anura) Eggs.- Summary.- Materials and Methods.- Results.- Discussion.- References.- 12 Urodele Egg Jelly and Fertilization.- Summary.- Materials and Methods.- Results and Discussion.- Conclusions.- References.- 13 Induction of the Acrosomal Reaction in Sperm from the White Sturgeon, AcipenserTransmontanus.- Summary.- Materials and Methods.- Results and Discussion.- Conclusions.- References.- 14 Sperm Glycosidase as a Plausible Mediator of Sperm Binding to the Vitelline Envelope in Ascidians.- Summary.- Experimental.- Discussion.- References.- 15 Structure, Assembly and Functions of the Surface Envelope (Fertilization Envelope) from Eggs of the Sea Urchin, StronglyocentrotusPurpuratus.- Summary.- Ultrastructure and Polypeptide Composition of the FE.- Ultrastructural and Biochemical Stages in FE Development.- VE Sperm Receptor and Modulation of Its Activity During the VE to FE Transition.- Concluding Remarks.- References.- 16 Characterization of the StrongylocentrotusPurpuratus Egg Cell Surface Receptor for Sperm.- Summary.- Materials and Methods.- Results and Discussion.- Conclusions.- References.- 17 Peptides Associated with Eggs: Mechanisms of Interaction with Spermatozoa.- Summary.- Materials and Methods.- Results.- Discussion.- References.- 18 Dephosphorylation of Sea Urchin Sperm Guanylate Cyclase During Fertilization.- Summary.- Materials and Methods.- Results and Disucssion.- Conclusions.- References.- 19 Steps in the Fertilization Process: Understanding and Control.- Summary.- References.- 20 Control of Fertilization by Immunization with Peptide Fragments of Sperm Specific LDH-C4.- Summary.- Fertility Reduction by Sperm Antigens.- Development of an Immunocontraceptive Technology: Sperm Specific LDH-C4.- References.- 21 Pathways to Immunocontraception: Biochemical and Immunological Properties of Glycoprotein Antigens of the Porcine Zona Pellucida.- Summary.- Isolation of Porcine Zonae Pellucidae.- Macromolecular Composition of the Porcine Zona Pellucida.- Comparative Aspects of Mammlian Zona Pellucida Structure.- Isolation of a Purified Porcine Zona Antigen (PPZA).- Antibodies to PPZA.- Isolation and Properties of 82K and 55K Antigens from SDS-Dissociated Nonreduced Porcine Zonae Pellucida.- References.- 22 Research Frontiers in Human In Vitro Fertilization.- Summary.- Endocrine Aspects.- Gamete Biology.- Embryonic Development and Implantation.- References.
Series Title: Advances in experimental medicine and biology, v. 207.
Responsibility: edited by Jerry L. Hedrick.

Abstract:

This book is derived from presentations made at the Symposium held at the University of California, Davis, on June 20-22, 1984, This 75th Anniversary Symposium was sponsored by the Division of Biological Sciences, Donald L. McLean, Dean, and was organized in celebration of the founding of the Davis campus of the University of California. I am indebted to the members of the Organizing Committee, W.H. Clark, R.D. Grey, A. Lopo, and U.A. Urch, who ably assisted in the organization and execution of the Symposium. Financial support was provided by the 75th Anniversary Committee and the Division of Biological Sciences, both of the Davis campus; by a grant from the California Sea Grant College Program, University of California, La Jolla; by an NIH Training Grant/Reproductive Biology; and, by a contribution from Jack Daniels Distillery out of Sacramento. The members of my research laboratory, N. Wardrip, D. Goldhawk, M. Bakos, L. Lindsay, B. Shew, K. Clark provided essential logistical support critical to the smooth and efficient running of the meetings.

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