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Molecular diagnostics in cytopathology : a practical handbook for the practicing pathologist

Author: Sinchita Roy-Chowdhuri; Paul A VanderLaan; John M Stewart; Gilda da Cunha Santos
Publisher: Cham, Switzerland : Springer, [2019]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The main focus of this book is to provide an overview of the principles of molecular diagnostics in context of cytopathology specimens together with a basic understanding and working knowledge of the available technology, platforms, and clinical applications. The initial sections of the book summarize the pre-analytic aspects of molecular testing, including cytology specimen preparation and handling, specimen  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Sinchita Roy-Chowdhuri; Paul A VanderLaan; John M Stewart; Gilda da Cunha Santos
ISBN: 9783319973975 3319973975
OCLC Number: 1076543106
Description: 1 online resource
Contents: Introduction: Overview of Current Molecular Diagnostic Testing on Cytology Samples.- The Cytology Specimen and Preparations: Advantages and Limitations.- Sample Acquisition and Test Requisition.- Pre-Analytic Workflow and Specimen Evaluation.- DNA-Based Sequencing Assays.- RNA-Based Assays.- FISH Testing of Cytology Specimens: Pre-Analytic, Analytic and Post-Analytic Considerations.- Molecular Cytopathology Correlations: Interpretation of Molecular Diagnostic Results.- Human Papillomavirus (HPV) Testing of Head and Neck Cancers.- Human Papillomavirus (HPV) Testing on Cervical Cytology Specimens.- Molecular Diagnostics in Lung Cytology.- Molecular Diagnostics in Thyroid Cytology.- Molecular Diagnostics in Breast Cytology.- Molecular Diagnostics in Salivary Gland Cytology.- Molecular Diagnostics in Pancreatic and Biliary Cytology.- Fluorescence In Situ Hybridization (FISH) Testing in Urinary Tract Cytology.- Molecular Diagnostics in Hematological Malignancies.- Molecular Diagnostics in Bone and Soft Tissue Tumors.- Molecular Diagnostics in Pediatric Cytopathology.- Molecular Cytopathology: Final Thoughts and Future Directions.
Responsibility: editors, Sinchita Roy-Chowdhuri, Paul A. VanderLaan, John M. Stewart, Gilda da Cunha Santos.

Abstract:

The main focus of this book is to provide an overview of the principles of molecular diagnostics in context of cytopathology specimens together with a basic understanding and working knowledge of the available technology, platforms, and clinical applications. The initial sections of the book summarize the pre-analytic aspects of molecular testing, including cytology specimen preparation and handling, specimen selection and evaluation, and workflow algorithms as well as the analytic considerations for a variety of nucleic acid and protein-based testing. The remaining section focuses on disease specific molecular testing for various organ-based applications. Molecular Diagnostics in Cytopathology: A Practical Handbook for the Practicing Pathologist serves as a useful resource for cytopathologists, surgical pathologists, molecular technologists, and all others dealing with the evolving field of molecular cytopathology. .

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