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Molecular mechanisms of xeroderma pigmentosum

Author: Shamim I Ahmad; Fumio Hanaoka
Publisher: New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2008.
Series: Advances in experimental medicine and biology, v. 637.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
To understand the molecular mechanisms of XP, XP mouse models have been used, and mice deficient in XPA, XPC, XPD, XPG, XPF, and XPA/CSB have been produced and analysed. This title includes a chapter that analyzes the world distribution of XP and shows that Japan has the highest incidence of XP and of varying complementation groups.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Molecular mechanisms of xeroderma pigmentosum.
New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2008
(DLC) 2008021297
(OCoLC)228114881
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Shamim I Ahmad; Fumio Hanaoka
ISBN: 9780387095998 0387095993
OCLC Number: 314175015
Description: 1 online resource (xxvii, 166 pages) : illustrations (some color).
Contents: Historical aspects of xeroderma pigmentosum and nucleotide excision repair / James E. Cleaver --
Clinical features of xeroderma pigmentosum / Ulrich R. Hengge and Steffen Emmert --
Xeroderma pigmentosum and skin cancer / Leela Daya-Grosjean --
XPA gene, its product and biological roles / Ulrike Camenisch and Hanspeter Nogeli --
XPB and XPD between transcription and DNA repair / Brian D. Beck, Dae-Sik Hah, and Suk-Hee Lee --
XPC: its product and biological roles / Kaoru Sugasawa --
The XPE gene of xeroderma pigmentosum : its product and biological roles / Drew Bennett and Toshiki Itoh --
XPF/ERCC4 and ERCC1 : their products and biological roles / Lisa D. McDaniel and Roger A. Schultz --
XPG: its products and biological roles / Orlando D. Schorer --
Xeroderma pigmentosum variant, XPV: its product and biological roles / Chikahide Masutani, Fumio Hanaoka, and Shamim I. Ahmad. Other proteins interacting with XP proteins / Steven M. Shell and Yue Zou --
The nucleotide excision repair of DNA in human cells and its association with xeroderma pigmentosum / Alexei Gratchev --
Roles of oxidative stress in xeroderma pigmentosum / Masaharu Hayashi --
Xeroderma pigmentosum : its overlap with trichothiodystrophy, Cockayne syndrome, and other progeroid syndromes / W. Clark Lambert, Claude E. Gagna, and Muriel W. Lambert --
Population distribution of xeroderma pigmentosum / Abdul Manan Bhutto and Sandra H. Kirk --
Progress and prospects of xeroderma pigmentosum therapy / Alain Sarasin --
Animal models of xeroderma pigmentosum / Xue-Zhi Sun [and others].
Series Title: Advances in experimental medicine and biology, v. 637.
Responsibility: edited by Shamim I. Ahmad, Fumio Hanaoka.

Abstract:

To understand the molecular mechanisms of XP, XP mouse models have been used, and mice deficient in XPA, XPC, XPD, XPG, XPF, and XPA/CSB have been produced and analysed. This title includes a chapter  Read more...

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