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Molecular targeting and signal transduction

Author: Rakesh Kumar, (Professor of Biotechnology)
Publisher: New York : Kluwer Academic Publishers, ©2004.
Series: Cancer treatment and research, v. 119.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Molecular targeting and signal transduction.
New York : Kluwer Academic Publishers, ©2004
(DLC) 2004051596
(OCoLC)55139823
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Rakesh Kumar, (Professor of Biotechnology)
ISBN: 1402078471 9781402078477 6610148317 9786610148318
OCLC Number: 55535545
Description: 1 online resource (1 volume).
Contents: Biology of the Epidermal Growth Factor Receptor Family --
Integrin Signaling in Cancer.-Regulators of Vascular Endothelial Growth Factor Expression in Cancer --
Integrin-Linked Kinase (ILK) in Combination Molecular Targeting --
p21-Activated Kinase 1: An Emerging Therapeutic Target --
Basis and Importance of Src as a Target in Cancer.-Therapeutic Targeting of the Receptor Tyrosine Kinase Met --
Nuclear Factor --
kB Activation Mediates Cellular Transformation, Proliferation, Invasion, Angiogenesis and Metastasis of Cancer --
The p53 Pathway: Targets for the Development of Novel Cancer Therapeutics --
Runx Protein Signaling in Human Cancers --
Signal Transduction Mediated by Cyclin D1: From Mitogens to Cell Proliferation: A Molecular Target with Therapeutic Potential --
Signal Transduction Pathways in Bcr-Abl Transformed Cells --
Estrogen Receptors and Anti-Estrogen Therapies --
Targeting Endothelin Axis in Cancer.-km23: A Novel TGFb Signaling Target Altered in Ovarian Cancer.
Series Title: Cancer treatment and research, v. 119.
Responsibility: edited by Rakesh Kumar.
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Abstract:

This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation.  Read more...

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