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THE NATURAL HISTORY OF RABIES, VOLUME 1.

Author: George M Baer
Publisher: Saint Louis : Elsevier Science, 2014.
Edition/Format:   eBook : Document : English : 2nd edView all editions and formats
Summary:
The Natural History of Rabies, Volume I explores the fundamental aspects of the rabies virus, including its growth, latency, morphology, chemistry, physical characteristics, and relationships with other viruses. It looks at the virus' in vivo pathogenesis and pathology, from entrance to transmission in the central nervous system (CNS) and subsequent exit. It also reviews current diagnostic methods including those  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Baer, George M.
THE NATURAL HISTORY OF RABIES, VOLUME 1.
Saint Louis : Elsevier Science, ©2014
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: George M Baer
ISBN: 9780323139700 0323139701
OCLC Number: 1044713919
Notes: I. Pathogenesis after Subcutaneous or Intramuscular Introduction of Virus.
Description: 1 online resource (477 pages)
Contents: Front Cover; The Natural History of Rabies; Copyright Page; Table of Contents; List of Contributors; Preface; Contents of Volume II; Chapter 1. History of Rabies; References; PART I: The Virus; Chapter 2. Morphology and Morphogenesis; I. Morphology of Rabies Virus; II. Morphogenesis of Rabies Virus; III. The Bearing of Morphology and Morphogenesis on the Placement of Rabies Virus in the Rhabdovirus Group; Acknowledgment; References; Chapter 3. Antigenic Composition of Rabies Virus; I. Introduction; II. Rabies Antigen in Infected Cells; III. Antigens of the Rabies Virion. IV. Antigens of Disrupted VirionsV. Soluble Antigen; VI. Conclusion; Acknowledgments; References; Chapter 4. Chemical Composition and Structure of Rabies Virus; I. Introduction; II. Properties of the Virion; III. Disruption of the Virus into Its Components; IV. The Viral RNA; V. Viral Structural Proteins; VI. Intracellular Virus and Viral Components; Acknowledgment; References; Chapter 5. Hemagglutinin of Rabies Virus; I. Introduction; II. Optimal Conditions for Preparation and Demonstration of Hemagglutinin; III. Characteristics of Hemagglutinin. IV. Relationship between Hemagglutinating and Immunizing Capacity of Rabies Virus ParticlesV. Hemagglutination Inhibition Test; References; Chapter 6. Passive Hemagglutination Test; I. Passive Hemagglutination Procedure; II. Advantages of the Passive Hemagglutination Test; III. Disadvantages of the Test; References; Chapter 7. Concentration and Purification; I. Introduction; II. Methods for Concentration; III. Methods of Purification; IV. Summary; References; Chapter 8. Rabies Virus Antigenic Relationships; I. Introduction. II. Antigenic Distinction between the Viruses of the Rabies Sero Group and Other RhabdovirusesIII. Rabies-Related Viruses; IV. Antigenic Relationships in the Rabies Group; V. Other Antigenic Variants of Rabies Virus; VI. Significance of Rabies-Related Viruses; References; PART II: Pathogenesis and Pathology; Chapter 9. Growth of Rabies Virus in Cell Culture; I. Introduction; II. Historical Review; III. Adaptation of Rabies Virus to Growth in Cell Culture; IV. Chronic Infection of Cell Culture Systems; V. Dynamics of Virus Replication in Vitro; VI. Virus-Specific Products of Infected Cells. VII. Virion-free Rabies Antigen (Soluble Antigen) (VFRA)VIII. Immune Lysis; IX. Production of Interferon in Rabies Virus-Infected Cells; X. Cytopathic Effect of Rabies Virus in Cell Cultures; XI. Optimal Conditions for the Production of Rabies Virus in High Titer; XII. Coinfection of Cells in Vitro with Rabies and Other Viruses; XIII. Effect of Metabolic Inhibitors on Virus Replication in Vitro; XIV. Alteration of Rabies Virus Phenotype as a Result of Passage in Cell Culture; Acknowledgment; References; Chapter 10. Pathogenesis to the Central Nervous System.

Abstract:

The Natural History of Rabies, Volume I explores the fundamental aspects of the rabies virus, including its growth, latency, morphology, chemistry, physical characteristics, and relationships with other viruses. It looks at the virus' in vivo pathogenesis and pathology, from entrance to transmission in the central nervous system (CNS) and subsequent exit. It also reviews current diagnostic methods including those used for antibody titration and for determination of virus presence. Organized into three sections encompassing 21 chapters, this volume begins with an overview of the history of.

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