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NETosis : immunity, pathogenesis and therapeutics

Author: Geeta Rai
Publisher: London : Elsevier, [2019] ©2019
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for  Read more...
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Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Geeta Rai
ISBN: 9780128163795 0128163798
OCLC Number: 1104080854
Description: 1 online resource (202 pages) : illustrations
Contents: Neutrophil extracellular trap formation: an introduction --
NETosis: mechanisms and antimicrobial strategies --
Factors regulating NETosis --
NETosis in neonates --
NETosis in autoimmunity --
NETosis in other diseases and therapeutic approaches.
Responsibility: Geeta Rai.

Abstract:

NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved.

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