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The Neutrophil: Cellular Biochemistry and Physiology.

Author: Maurice B Hallett
Publisher: Boca Raton, FL : CRC Press, 2017.
Edition/Format:   eBook : Document : English : First editionView all editions and formats
Summary:
"A synthesis and collation of the recent material regarding the role of the neutrophil in basic pathological processes is presented in this volume. The mechanisms of chemotaxis, secretion, phagocytosis, intracellular killing, oxygen radical production and arachidonate production are comprehensively reviewed. Stimulus response coupling in the neutrophil, with chapters on intracellular Ca2+, C-Kinase, phospholipid  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Maurice B Hallett
ISBN: 9781351077200 1351077201 9781351085656 1351085654
OCLC Number: 1019727944
Description: 1 online resource (276 pages)
Contents: 1. The Significance of Stimulus-Response Coupling in the Neutrophil for Physiology and Pathology 2. Characteristics and Mechanisms of Secretion by Neutrophils 3. Biophysics of Leukocytes: Neutrophil Chemotaxis; Characteristics and Mechanisms 4. The Molecular Mechanism of Oxygen Reduction by the Neutrophil Oxidase 5. Mobilization, Metabolism, and Bio-logical Effects of Eicosanoids in Polymorphonuclear Leuko-cytes 6. The Cortical Actin Filament Network of Neutrophil Leukocytes during Phagocytosis and Chemotaxis 7. The Role of Inositol Phospholipid Metabolism and Diacylglycerol Production in Neutrophil Signal Transduction 8. Role of Calcium in Neutrophil Activation 9. Ca2+-Dependent and Independent Mechanisms in Neutrophil Activation; Roles of Kinase-C, Diacyl-glycerol, and Unidentified Intracellular Messengers 10. Ion Transport in Phagocytes

Abstract:

"A synthesis and collation of the recent material regarding the role of the neutrophil in basic pathological processes is presented in this volume. The mechanisms of chemotaxis, secretion, phagocytosis, intracellular killing, oxygen radical production and arachidonate production are comprehensively reviewed. Stimulus response coupling in the neutrophil, with chapters on intracellular Ca2+, C-Kinase, phospholipid metabolism, microfilaments and membrane electrophysiology are extensively discussed. Each chapter provides a critical review by experts with over 1,000 cited references. Invaluable to graduate students and medical and scientific researchers, this book provides a unique, up-to-date account of cellular biochemistry and physiology of the neutrophil."--Provided by publisher.

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