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Nuclear factor kB : regulation and role in disease

Author: Rudi Beyaert
Publisher: Dordrecht ; Boston : Kluwer Academic Publishers, 2003.
Edition/Format:   Print book : EnglishView all editions and formats

Seventeen years after its initial description, nuclear factor-KB (NF-KB) endures as one of the most studied transcription factors.


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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Rudi Beyaert
ISBN: 1402014341 9781402014345
OCLC Number: 52377605
Description: xi, 426 pages : illustrations ; 25 cm
Contents: Contributors. Preface. Activators and Target Genes of Rel/NF-kappaB Transcription Factors - From Bench to Bedside; T. Loop, H.L. Pahl. NF-kappaB Activation by Tumor Necrosis Factor and Interleukin-1; I. Carpentier, S. Janssens, K. Heyninck, R. Beyaert. NF-kappaB Activation by CARD Proteins; J.-L. Poyet, E.S. Alnemri. Viruses as Intruders in the Rel/NF-kappaB Signaling Pathway; T.D. Gilmore, G. Mosialos. The IkappaB Kinase (IKK) Complex; U. Senftleben, M. Karin. The Role of Ubiquitin in NF-kappaB Signaling; L. Deng, Z.J. Chen. New Insights into the Regulation of NF-kappaB - Roles for Phosphorylation and Acetylation of NF-kappaB Subunits; A. O'Mahony, L.F. Chen, W.C. Greene. The Structural Biology of NF-kappaB; T. Huxford, G. Ghosh. Tools to Interfere with NF-kappaB Activation; Y. Yamamoto, U.N. Verma, R.B. Gaynor. Regulation of NF-kappaB by Glucocorticoids; K. De Bosscher, W. Vanden Berghe, G. Haegeman. Genetic Analysis of NF-kappaB-dependent Signaling Pathways in Mammalian Cells; X. Li, G.R. Stark. Delineation of NF-kappaB Signaling by Gene Targeting; N. Suzuki, M. Bonnard, S. Suzuki, W.-C. Yeh. The Role of NF-kappaB in Inflammatory Diseases; E. Andreakos, I. Udalova, S. Sacre, B.M. Foxwell. NF-kappaB in Genetic Disorders; G. Courtois, A. Israel. NF-kappaB in the Vascular System; R. De Martin. NF-kappaB in T-lymphocyte Biology; O. Dienz, S. Bacher, M.L. Schmitz. NF-kappaB in the Nervous System; B. Kaltschmidt, C. Kaltschmidt. NF-kappaB in Oncogenesis and as a Target for Cancer Therapy; A.S. Baldwin Jr. Control of Immunity by Rel Proteins in Drosophila; P. Georgel. Index.
Responsibility: edited by Rudi Beyaert.
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