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Oral microbiology and immunology

Author: Richard J Lamont; George Hajishengallis; Hyun Koo, (Professor of dental medicine); Howard F Jenkinson
Publisher: Washington, DC : ASM Press, [2019]
Edition/Format:   eBook : Document : English : Third editionView all editions and formats
Summary:
The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Oral microbiology and immunology
Washington, DC : ASM Press, [2019]
(DLC) 2019003807
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Richard J Lamont; George Hajishengallis; Hyun Koo, (Professor of dental medicine); Howard F Jenkinson
ISBN: 9781555819996 1555819990
OCLC Number: 1088600851
Description: 1 online resource
Contents: Cover; Table of Contents; Contributors; Preface; About the Editors; SECTION I. GENERAL PRINCIPLES OF ORAL MICROBIOLOGY AND IMMUNOLOGY; 1. General Microbiology; Introduction; Biological Classification Scheme; Bacterial Classification; Bacterial Architecture; Membranes; Cell Wall Peptidoglycan; Lipopolysaccharides; Lipoteichoic Acids; Other Important Components Produced by Bacteria; Capsule; Fimbriae and Pili; Fibrillar Layers; Flagella; Vesicles; Surface Layers; Endospores; Genetic Organization in Bacteria; The Bacterial Chromosome; Chromosome Replication in Bacteria; Gene Transfer in Bacteria Bacterial Growth and NutritionGrowth; Nutrient Acquisition; Environmental Sensing; Secretion; Introduction to Fundamental Concepts in Oral Microbial Ecology; Microbial Biofilms; Microbial Cooperativity; Microbial Antagonism; Polymicrobial Communities; Ecology of the Oral Microbiota and Development of Oral Diseases; KEY POINTS; 2. The Immune System and Its Functions; Introduction-What Is Immunity?; Innate and Adaptive Immunity; BOX: Cells of the Immune System; Immune Recognition Mechanisms; Innate Immune Recognition: Pattern Recognition Receptors; Adaptive Immune Recognition: Antigen Receptors Induction and Stages of the Immune ResponseTailored Immunity Requires Specialized Subsets of Immune Cells; Hallmark Properties of Immunity; Properties of Adaptive Immunity; Properties of Innate Immunity; KEY POINTS; FURTHER READING; 3. The Oral Environment; Introduction; Oral Diseases; General Features of the Oral Environment; Teeth; The Oral Soft Tissues (Periodontium, Oral Mucosa, and Tongue); Physical and Host Parameters Affecting Oral Microbial Colonization; Temperature; pH; Oxygen; Mechanical Abrasive Forces; Fluid Flow; Host Age; The Oral Microbiota Tooth (Dental) Plaque: Early Determinants of Plaque FormationCalculus; The Mucosal Microbiota; Recent Concepts of Dental Biofilm Formation; Saliva and the Salivary Proteome; Saliva-Microbe Interactions; Clearance of Bacteria from the Oral Cavity: Agglutinins; Pellicle Adhesion Receptors; Antimicrobial Components in Saliva; Antiviral Components in Saliva; Saliva as a Source of Bacterial Nutrition; Gingival Crevicular Fluid; KEY POINTS; FURTHER READING; 4. Isolation, Classification, and Identification of Oral Bacteria; Introduction; Diversity of the Oral Microbiota The Ribosomal 16S rRNA Gene and Bacterial Identification and Classification16S rRNA Genes and Phylogeny; Sampling Oral Bacteria and Recovery of Bacterial DNA from Samples; Identifying Oral Bacteria Using Molecular Techniques; PCR Detection; Quantitative PCR; DNA Hybridization Assays; Ribosomal 16S rRNA Gene Cloning and Sequence Analysis; Next-Generation Sequencing of 16S rRNA Genes; Metagenomic Sequence Analysis; Species and Strains of Oral Bacteria; Naming of Bacteria and Molecular Analysis; Direct Observation of Oral Bacteria; Cultivation of Oral Bacteria; Oxygen Requirements; Culture Media
Responsibility: Richard J. Lamont, George N. Hajishengallis, Hyun (Michel) Koo, Howard F. Jenkinson.

Abstract:

The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis and dental caries. Against this backdrop, the third edition of Oral Microbiology and Immunology has been substantially expanded and rewritten by an international team of authors and.

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"The textbook is a great resource for undergraduate and graduate dental students, dental educators, and researchers alike. It builds upon principles of general microbiology and immunology and, Read more...

 
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