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Pancreatic Islet Isolation : From the Mouse to the Clinic

Author: Miriam Ramírez-Domínguez
Publisher: Cham : Springer International Publishing : Imprint : Springer, 2016.
Series: Advances in experimental medicine and biology, 938.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Miriam Ramírez-Domínguez
ISBN: 9783319398242 3319398245 9783319398228 3319398229
OCLC Number: 1048188195
Description: 1 online resource (XII, 123 pages 31 illustrations in color.) : online resource
Contents: Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez --
The Different Faces of the Pancreatic Islets, Midhat H. Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren --
Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez --
Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst --
Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman --
Necessities for a Clinical Islet Program, Wayne John Hawthorne --
Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew --
Index.
Series Title: Advances in experimental medicine and biology, 938.
Responsibility: edited by Miriam Ramírez-Domínguez.

Abstract:

Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate "work of a  Read more...

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