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Document Type: | Book |
---|---|
All Authors / Contributors: |
Henry A Erlich |
ISBN: | 0333489489 9780333489482 093585956X 9780935859560 |
OCLC Number: | 19267540 |
Description: | ix, 246 pages |
Contents: | Part 1 Introduction to the PCR: history of PCR development; description of the PCR method - basic principles and properties of the PCR; thermostable DNA polymerases; automation; sample preparation. Part 2 Research applications - brief overview: direct sequencing using PCR; preparation of specific DNA fragments using PCR; detection of gene expression; genetic mapping using PCR amplification of individual gametes. Part 3 Diagnostic applications - brief overview: detection of pathogens; diagnosis of monogenic genetic diseases; HLA DNA typing and disease susceptibility; forensic applications; detection of activated oncogenes; future developments and applications. |
Series Title: | Breakthroughs in molecular biology. |
Responsibility: | Henry A. Erlich editor. |
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