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Personalized predictive modeling in Type 1 diabetes

Author: Eleni I Georga; Dimitrios Ioannou Fotiadis; Stelios K Tigas
Publisher: London : Academic Press, an imprint of Elsevier, [2018]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or  Read more...
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Genre/Form: Electronic books
Electronic book
Additional Physical Format: (OCoLC)960895690
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Eleni I Georga; Dimitrios Ioannou Fotiadis; Stelios K Tigas
ISBN: 9780128051467 0128051469
OCLC Number: 1013541224
Description: 1 online resource
Contents: 1. Introduction2. Data-Driven Prediction of Glucose Concentration in Type 1 Diabetes3. Linear Models of Glucose Concentration4. Non-linear Models of Glucose Concentration5. Prediction Models of Hypoglycaemia6. Adaptive Glucose Prediction Models7. Anticipatory Mobile Systems in Diabetes8. Conclusions and Future Trends
Responsibility: Eleni I. Georga, Dimitrios I. Fotiadis, Stelios K. Tigas.

Abstract:

Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures.

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