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Pharmaceutical powder and particles

Author: Anthony J Hickey; Stefano Giovagnoli
Publisher: Cham, Switzerland : Springer, [2018] ©2018
Series: AAPS introductions in the pharmaceutical sciences.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing.  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Hickey, Anthony J., 1955-
Pharmaceutical powder and particles.
Cham, Switzerland : Springer, [2018]
(OCoLC)1030905864
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Anthony J Hickey; Stefano Giovagnoli
ISBN: 9783319912202 3319912208 9783319912219 3319912216 9783030082017 3030082016
OCLC Number: 1048621615
Description: 1 online resource
Contents: Intro; Preface; Contents; Chapter 1: Introduction; References; Chapter 2: Solid-State Chemistry; Composition; Structure; Imperfections; Conclusion; References; Chapter 3: Crystallization; Nucleation and Nucleating Agents; Crystal Composition and Crystal Engineering; Polymorphism; Water of Crystallization; Conclusion; References; Chapter 4: Physical Properties Characterization; Surface Area; Charge; Polymorphism; Moisture Content; Hygroscopicity; Impurities; Conclusion; References; Chapter 5: Particle Size and Distribution; Morphology and Size; Optical Diameters; Projected Area. Surface Area DiameterVolume Diameter; Dynamic Diameters; Sedimentation; Field Flow Fractionation; Aerodynamic; Laser Diffraction; Quasi Elastic (Photon Correlation Spectroscopy, Dynamic) Light Scattering; Population Statistics; Mathematical Distributions; Basis for Expression; Number/Count; Volume; Mass; Hatch-Choate Equations; Special Considerations; Conclusion; References; Chapter 6: Particle Size Measurement; Dimensions; Microscopy; Light; Electron Microscopy; Other Microscopy Methods; Data Collection; Light Scattering; Laser Diffraction; Time-of-Flight Measurement. Laser Doppler VelocimetryElectrical Sensing Zone; Dynamic Methods; Sieving; Sedimentation; Aerodynamic; Quasi-elastic (or Photon Correlation Spectroscopy or Dynamic) Light Scattering; Product-Specific Particle Size Analysis Considerations; Conclusion; References; Chapter 7: Fundamentals of Particle Interactions; Fundamental Forces of Particle Interaction; Nature of Aggregation; Conclusion; References; Chapter 8: Powder and Particle-Dependent Traditional Manufacturing Processes (Unit Operations); Drying; Milling; Blending; Filling; Sampling; Stability; Conclusion; References. Chapter 9: Biopharmaceutical ProcessesBioavailability; Dissolution; Conclusion; References; Chapter 10: Recent and Evolving Manufacturing Processes; Spray-Drying Technology; Supercritical Fluid Methods; Particle Replication in Non-wetting Templates (PRINT) Technology; 3-D Printing; Conclusion; References; Chapter 11: Quality by Design for Particulate Systems; Manufacturing and Characterization; Experimental Design; Multivariate Statistics; Process Analytical Technology; Critical Quality Attributes; Risk Assessment/Management; Other Considerations; Conclusion; References. Chapter 12: General ConclusionParticles; Particle Systems; Conclusion; Index.
Series Title: AAPS introductions in the pharmaceutical sciences.
Responsibility: Anthony J. Hickey, Stefano Giovagnoli.

Abstract:

This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future  Read more...

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