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Phenotypic screening : methods and protocols

Author: Bridget K Wagner
Publisher: New York, N.Y. : Humana Press : Springer, [2018] ©2018
Series: Methods in molecular biology (Clifton, N.J.), v. 1787.
Edition/Format:   eBook : Document : EnglishView all editions and formats

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Genre/Form: Laboratory Manual
Electronic books
Additional Physical Format: Print version:
Phenotypic screening.
New York, N.Y. : Springer, ©2018
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Bridget K Wagner
ISBN: 9781493978472 1493978470
OCLC Number: 1035016515
Description: 1 online resource (xii, 280 pages) : illustrations (some color)
Contents: Nutrient stress small-molecule screening platform for Escherichia coli / Sara S. El Zahed, Garima Kumar, Madeline Tong, and Eric D. Brown --
Validation and development of an Escherichia coli riboflavin pathway phenotypic screen hit as a small-molecule ligand of the flavin mononucleotide riboswitch / Carl J. Balibar, Artjohn Villafania, Christopher M. Barbieri, Nick Murgolo, Terry Roemer, Hao Wang, and John A. Howe --
Phenotypic screening of small molecules with antimalarial activity for three different parasitic life stages / Nobutaka Kato, Sandra March, Sangeeta N. Bhatia, and Matthias Marti --
Phenotypic screening for inhibitors of a mutant thrombopoietin receptor / Anna Ngo, Ann Koay, Christian Pecquet, Carmen C. Diaconu, David A. Jenkins, Andrew K. Shiau, Stefan N. Constantinescu, and Meng Ling Choong --
Cell-based assay for mitotic spindle orientation / Elina Glaubke and Holger Bastians --
Isolation of skeletal muscle stem cells for phenotypic screens for modulators of proliferation / Aaron C. Hinken and Andrew N. Billin --
Cell-based methods to identify inducers of human pancreatic beta-cell proliferation / Courtney A. Ackeifi, Ethan A. Swartz, and Peng Wang --
High-content imaging phenotypic screen for neurogenesis using primary neural progenitor cells / Li Sharon Wu and Jingjun Li --
Discovery of modulators of adipocyte physiology using fully functionalized fragments / Andrea Galmozzi, Christopher G. Parker, Bernard P. Kok, Benjamin F. Cravatt, and Enrique Saez --
Ancient genetic networks of obesity : whole-animal automated screening for conserved fat regulators / Wenfan Ke, Anna Drangowska-Way, Daniel Katz, Karsten Siller, and Eyleen J. O'Rourke --
Modulation of threat response in larval zebrafish / Andrew J. Rennekamp --
PLA-iRoCS pipeline for the localization of protein-protein interactions in situ / Taras Pasternak, William Teale, Thorsten Falk, Benedetto Ruperti, and Klaus Palme --
High-dimensional profiling : the theta comparative cell scoring method / Scott J. Warchal, John C. Dawson, and Neil O. Carragher --
Accessing the open PHACTS discovery platform with workflow tools / Daniela Digles, Andrei Caracoti, and Edgar Jacoby --
Quantitative prioritization of tool compounds for phenotypic screening / Yuan Wang and Jeremy L. Jenkins --
Quantitative systems pharmacology approach to infer pathways involved in complex disease phenotypes / Mark E. Schurdak, Fen Pei, Timothy R. Lezon, Diane Carlisle, Robert Friedlander, D. Lansing Taylor, and Andrew M. Stern --
Phenotype-based high-content screening using fluorescent chemical bioprobes : lipid droplets and glucose uptake quantification in live cells / Young-Hee Shin and Seung Bum Park --
Developing high-throughput assays to analyze and screen electrophysiological phenotypes / Jen Q. Pan, David Baez-Nieto, Andrew Allen, Hao-Ran Wang, and Jeffrey R. Cottrell --
Testing susceptibility of patient-derived organoid cultures to therapies : pharmacotyping / Richard A. Burkhart, Lindsey A. Baker, and Herve Tiriac --
Techniques to enable 1536-well phenotypic screening / Sinead Knight, Helen Plant, Lisa McWilliams, and Mark Wigglesworth.
Series Title: Methods in molecular biology (Clifton, N.J.), v. 1787.
Responsibility: edited by Bridget Wagner.


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