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Physiology and pathophysiology of digestion. Part 2

Author: D Neil Granger; James Morris; Peter R Kvietys
Publisher: [San Rafael, California] : Morgan & Claypool, 2018.
Series: Colloquium digital library of life sciences.; Colloquium series on integrated systems physiology, # 83.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This collaboration of two physiologists and a gastroenterologist provides medical and graduate students, medical and surgical residents, and subspecialty fellows a comprehensive summary of digestive system physiology and addresses the pathophysiological processes that underlie some GI diseases. The textual approach proceeds by organ instead of the traditional organization followed by other GI textbooks. This  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: D Neil Granger; James Morris; Peter R Kvietys
ISBN: 1615047883 9781615047888
OCLC Number: 1054827941
Notes: Part of: Colloquium digital library of life sciences.
Title from PDF title page (viewed on September 27, 2018).
Description: 1 online resource (1 PDF (xxiii, 112 pages)) : illustrations
Contents: 4. The stomach --
Introduction --
General anatomical features of the stomach --
Gastric secretion --
Mucosal glands --
Acid secretion --
Pepsinogen and lipase secretion --
Functions of gastric acid and pepsin --
Mucus secretion --
Functions of mucus --
Integrated regulation of gastric secretion --
Interprandial (basal) acid secretion --
Postprandial secretion --
Gastric motility --
Microscopic anatomy of the muscularis --
Electrical and contractile activity of smooth muscle --
Gastric accommodation --
Transpyloric movement of chyme --
Gastric emptying --
Integrated regulation of gastric motility --
Interprandial (basal) motility --
Postprandial motility --
Overview of the gastric response to a meal --
Gastric blood flow --
Gastric mucosal growth --
Gastric mucosal defense --
Vomiting (emesis) --
Pain sensations from the stomach --
Pathophysiology and clinical correlations --
Peptic ulcer diseases --
Helicobacter pylori (H. pylori) --
Nonsteroidal anti-inflammatory drugs (NSAIDs) --
Gastroparesis (impaired gastric emptying) --
References. 5. The pancreas --
Introduction --
Anatomy --
Regulation of pancreatic mass --
Composition and formation of pancreatic juice --
Electrolytes --
Proteins --
Regulation of pancreatic secretion --
Endocrine and paracrine regulation --
Neural/neurocrine regulation --
Potentiation of secretory responses --
Feedback regulation of pancreatic secretion --
Overview of pancreatic secretory response to meals --
Basal secretion --
Cephalic phase of secretion --
Gastric phase of secretion --
Intestinal phase of secretion --
Functions of pancreatic juice --
Bicarbonate --
Enzymes --
The pancreatic circulation --
Functional implications of a portal circulation --
Role of the microcirculation in pancreatic secretion --
Pancreatic pain --
Pathophysiology and clinical correlations --
References. 6. The liver and biliary tree --
Introduction --
Functional anatomy of the liver and biliary tree --
Macroscopic anatomy --
Microscopic anatomy --
Hepatocyte growth and regeneration --
Composition of bile --
Hepatic bile --
Gallbladder bile --
Mechanisms of hepatic bile formation --
Canalicular bile formation --
Bile acid-dependent secretion --
Bile acid-independent secretion --
Ductal component of bile flow --
The gallbladder: anatomy and function --
Water and electrolyte transport --
Motor functions --
The enterohepatic circulation --
Fate of bile salts in the intestine --
Transport of absorbed bile salts to liver and resecretion into bile --
Regulation of the biliary system --
Bile salt concentration in portal blood --
Gastrointestinal hormones --
Secretin --Cholecystokinin --
Other hormones --
Nervous influences --
Parasympathetics --
Sympathetics --
The hepatic circulation --
Liver and biliary pain --
Pathophysiology and clinical correlations --Gallstones --
Conditions associated with hepatocellular injury --
References --
Author biographies.
Series Title: Colloquium digital library of life sciences.; Colloquium series on integrated systems physiology, # 83.
Responsibility: D. Neil Granger, James Morris, Peter R. Kvietys.

Abstract:

This collaboration of two physiologists and a gastroenterologist provides medical and graduate students, medical and surgical residents, and subspecialty fellows a comprehensive summary of digestive system physiology and addresses the pathophysiological processes that underlie some GI diseases. The textual approach proceeds by organ instead of the traditional organization followed by other GI textbooks. This approach lets the reader track the food bolus as it courses through the GI tract, learning on the way each organ's physiologic functions as the bolus directly or indirectly contacts it. The book is divided into three parts: 1) Chapters 1-3 include coverage of basic concepts that pertain to all (or most) organs of the digestive system, salivation, chewing, swallowing, and esophageal function, 2) Chapters 4-6 are focused on the major secretory organs (stomach, pancreas, liver) that assist in the assimilation of a meal, and 3) Chapters 7 and 8 address the motor, transport, and digestive functions of the small and large intestines. Each chapter includes its own pathophysiology and clinical correlation section that underscores the importance of the organ's normal function.

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