Plant lectins (Book, 1991) []
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Plant lectins

Plant lectins

Author: A Pusztai
Publisher: Cambridge ; New York : Cambridge University Press, 1991.
Series: Chemistry and pharmacology of natural products.
Edition/Format:   Print book : EnglishView all editions and formats
"This volume surveys the chemistry, biochemistry, biosynthesis, metabolism and pharmacological properties of lectins. Lectins, which are most commonly found in plants, are widespread natural products with striking biological activities. Their specific ability to recognize and bind to simple or complex saccharides facilitates their role as effective information protein molecules. As agents of cell recognition,  Read more...
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Genre/Form: Aufsatzsammlung
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: A Pusztai
ISBN: 0521328241 9780521328241
OCLC Number: 24212489
Description: vii, 263 pages : illustrations ; 24 cm
Contents: Acknowledgements --
Introduction (starting p. 1) --
1 Lectins and their specificity (starting p. 3) --
D-mannose/D-glucose-specific lectins (starting p. 4) --
N-acetyl-D-glucosamine-binding lectins (starting p. 9) --
N-acetyl-D-galactosamine/D-galactose-binding lectins (starting p. 14) --
Ricinus communis lectins (starting p. 15) --
Soyabean (Glycine max) agglutinin (starting p. 20) --
Phaseolus vulgaris lectins (PHA) (starting p. 24) --
L-fucose-binding lectins (starting p. 30) --
2 Structure of lectins (starting p. 32) --
Primary sequences (starting p. 32) --
Metal binding sites (starting p. 35) --
Hydrophobic sites (starting p. 36) --
Glycosylation sites (starting p. 37) --
Carbohydrate-binding sites (starting p. 37) --
Three-dimensional structure (starting p. 37) --
Conclusions (starting p. 38) --
3 Localization and biosynthesis in plants (starting p. 39) --
Localization in the plant and cellular location (starting p. 39) --
Seeds (starting p. 39) --
Vegetative parts (starting p. 43) --
Biosynthesis of plant lectins (starting p. 50) --
4 Biological functions in plants (starting p. 57) --
Interactions with endogenous receptors (starting p. 57) --
Interactions with exogenous receptors (starting p. 59) --
Defence against microorganisms and potential predators (starting p. 60) --
Legume-Rhizobium symbiosis (starting p. 64) --
Miscellaneous functions (starting p. 70) --
5 Effects on blood cells (starting p. 74) --
Agglutination (starting p. 74) --
Mitogenic stimulation of lymphocytes (starting p. 78) --
Immunosuppression (starting p. 95) --
Lectin-dependent blood cell cytotoxicity and phagocytosis (starting p. 101) --
Lectin-induced mast cell reactions (starting p. 102) --
6 General effects on animal cells (starting p. 105) --
Insulin-mimicking effects on adipocytes and other cells (starting p. 105) --
Effects of lectins on cells of the digestive tract (starting p. 107) --
Lectins in foods (starting p. 108) --
The nutritional toxicity of PHA (starting p. 111) --
Effects of PHA on the digestive tract in vivo (starting p. 113) --
Effects of other lectins on cells of the small intestine (starting p. 159) --
Transport of lectins through the membranes of the adult gut --
a potential system for the oral delivery of drugs (starting p. 179) --
Interactions with nerve cells and transneural transport of lectins (starting p. 183) --
Miscellaneous interactions of lectins with cells and their underlying structural elements (starting p. 190) --
Cytotoxins --
magic bullets --
immunotoxins (starting p. 199) --
References (starting p. 206) --
Glossary (starting p. 251) --
Index (starting p. 253)
Series Title: Chemistry and pharmacology of natural products.
Responsibility: A. Pusztai.
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Lectins are natural products found mainly in plants. Their properties are examined in this book.  Read more...


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"...can be recommended as an invaluable source of information for the more advanced student and the specialist whose research involves the use of lectins..." Quarterly Review of Biology

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