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| Genre/Form: | Aufsatzsammlung |
|---|---|
| Material Type: | Internet resource |
| Document Type: | Book, Internet Resource |
| All Authors / Contributors: |
A Pusztai |
| ISBN: | 0521328241 9780521328241 |
| OCLC Number: | 24212489 |
| Description: | vii, 263 pages : illustrations ; 24 cm |
| Contents: | Acknowledgements -- Introduction (starting p. 1) -- 1 Lectins and their specificity (starting p. 3) -- D-mannose/D-glucose-specific lectins (starting p. 4) -- N-acetyl-D-glucosamine-binding lectins (starting p. 9) -- N-acetyl-D-galactosamine/D-galactose-binding lectins (starting p. 14) -- Ricinus communis lectins (starting p. 15) -- Soyabean (Glycine max) agglutinin (starting p. 20) -- Phaseolus vulgaris lectins (PHA) (starting p. 24) -- L-fucose-binding lectins (starting p. 30) -- 2 Structure of lectins (starting p. 32) -- Primary sequences (starting p. 32) -- Metal binding sites (starting p. 35) -- Hydrophobic sites (starting p. 36) -- Glycosylation sites (starting p. 37) -- Carbohydrate-binding sites (starting p. 37) -- Three-dimensional structure (starting p. 37) -- Conclusions (starting p. 38) -- 3 Localization and biosynthesis in plants (starting p. 39) -- Localization in the plant and cellular location (starting p. 39) -- Seeds (starting p. 39) -- Vegetative parts (starting p. 43) -- Biosynthesis of plant lectins (starting p. 50) -- 4 Biological functions in plants (starting p. 57) -- Interactions with endogenous receptors (starting p. 57) -- Interactions with exogenous receptors (starting p. 59) -- Defence against microorganisms and potential predators (starting p. 60) -- Legume-Rhizobium symbiosis (starting p. 64) -- Miscellaneous functions (starting p. 70) -- 5 Effects on blood cells (starting p. 74) -- Agglutination (starting p. 74) -- Mitogenic stimulation of lymphocytes (starting p. 78) -- Immunosuppression (starting p. 95) -- Lectin-dependent blood cell cytotoxicity and phagocytosis (starting p. 101) -- Lectin-induced mast cell reactions (starting p. 102) -- 6 General effects on animal cells (starting p. 105) -- Insulin-mimicking effects on adipocytes and other cells (starting p. 105) -- Effects of lectins on cells of the digestive tract (starting p. 107) -- Lectins in foods (starting p. 108) -- The nutritional toxicity of PHA (starting p. 111) -- Effects of PHA on the digestive tract in vivo (starting p. 113) -- Effects of other lectins on cells of the small intestine (starting p. 159) -- Transport of lectins through the membranes of the adult gut -- a potential system for the oral delivery of drugs (starting p. 179) -- Interactions with nerve cells and transneural transport of lectins (starting p. 183) -- Miscellaneous interactions of lectins with cells and their underlying structural elements (starting p. 190) -- Cytotoxins -- magic bullets -- immunotoxins (starting p. 199) -- References (starting p. 206) -- Glossary (starting p. 251) -- Index (starting p. 253) |
| Series Title: | Chemistry and pharmacology of natural products. |
| Responsibility: | A. Pusztai. |
| More information: |
Abstract:
Lectins are natural products found mainly in plants. Their properties are examined in this book.
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Publisher Synopsis
"...can be recommended as an invaluable source of information for the more advanced student and the specialist whose research involves the use of lectins..." Quarterly Review of Biology
