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Platelet Membrane Glycoproteins

Author: James N George; Alan T Nurden; David R Phillips
Publisher: Boston, MA : Springer US, 1985.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
It was just about ten years ago that platelet membrane glycoproteins were first characƯ terized and their abnormalities in congenital bleeding disorders first recognized. DurƯ ing this decade there has been a remarkable growth in our understanding of the structure and membrane organization of the platelet surface glycoproteins, their inƯ teractions with external ligands during the process of hemostasis, and their  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: James N George; Alan T Nurden; David R Phillips
ISBN: 1468448803 9781468448801 9781468448825 146844882X
OCLC Number: 1058205936
Language Note: English.
Description: 1 online resource (XX, 420 pages)
Contents: I. Introduction --
1. Plasma Membrane Receptors and Platelet Response --
II. Plasma Membrane and Membrane Glycoprotein Structure and Function --
2. Structural and Molecular Properties of Platelet Membrane Systems --
3. Glycoproteins of the Platelet Plasma Membrane --
4. Organization of Glycoproteins within the Platelet Plasma Membrane --
5. Structure and Function of Platelet Membrane Glycoproteins as Studied by Crossed Immunoelectrophoresis --
6. Platelet Membrane Electrical Potential: Its Regulation and Relationship to Platelet Activation --
III. Interaction of Platelet Membrane Glycoproteins With The Extracellular Environment --
7. Receptors for Platelet Agonists --
8. Secreted Alpha Granule Proteins: The Race for Receptors --
9. The Platelet-Fibrinogen Interaction --
10. Platelet-von Willebrand Factor Interactions --
11. Molecular Mechanisms of Platelet Adhesion and Platelet Aggregation --
12. Lectin-Carbohydrate Binding as a Model for Platelet Contact Interactions --
IV. Interactions of Platelet Membrane Glycoproteins with the Intracellular Cytoskeleton --
13. The Organization of Platelet Contractile Proteins --
14. The Mechanism of Clot Retraction --
V. Platelet Membrane Glycoprotein Immunology and Abnormalities --
15. Immunology of the Platelet Surface --
16. Glycoprotein Defects Responsible for Abnormal Platelet Function in Inherited Platelet Disorders --
VI. Conclusion --
17. The Role of Membrane Glycoproteins in Platelet Formation, Circulation, and Senescence: Review and Hypotheses.
Responsibility: edited by James N. George, Alan T. Nurden, David R. Phillips.

Abstract:

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Primary Entity

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